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Table 3 Detection and distribution of H. pylori and its virulence genes in patients with various gastroduodenal disease outcomes

From: Detection of Helicobacter pylori and its virulence genes (cagA, dupA, and vacA) among patients with gastroduodenal diseases in Chris Hani Baragwanath Academic Hospital, South Africa

 

Disease conditions

 

Normal mucosal (%)

Pan gastritis (%)

Peptic ulcer (%)

Gastric erosion (%)

Hemorrhages and polyps (%)

Gastric cancer (%)

Total (%)

n = 17 (3.8)

n = 338 (76.1)

n = 55 (12.4)

n = 23 (5.2)

n = 8 (1.8)

n = 3 (0.7)

n = 444 (100)

H. pylori positive

9 (3.8)

180 (76.9)

31 (13.2)

11 (4.7)

3 (1.3)

0 (0)

234 (100)

cagA

7 (4.8)

111 (76.5)

17 (11.7)

8 (5.5)

2 (1.4)

0 (0)

145 (100)

dupA

5 (4.0)

94 (75.2)

15 (12.0)

9 (7.2)

2 (1.6)

0 (0)

125 (100)

vacAs1

8 (5.2)

111 (71.6)

26 (16.8) *

7 (4.5)

3 (1.9)

0 (0)

155 (100)

vacAs2

1 (2.1)

38 (80.9)

5 (10.6)

3 (6.4)

0 (0)

0 (0)

47 (100)

vacAm1

6 (3.7)

123 (75.9)

23 (14.2)

7 (4.3)

3 (1.9)

0 (0)

162 (100)

vacAm2

3 (6.0)

37 (74.0)

7 (14.0)

3 (6.0)

0 (0)

0 (0)

50 (100)

vacAs1/m1

6 (4.5)

97 (73.5)

20 (15.2)

6 (4.5)

3 (2.3)

0 (0)

132 (100)

vacAs1/m2

2 (9.1)

13 (59.0)

2 (9.1)

5 (22.7) *

0 (0)

0 (0)

22 (100)

vacAs2/m1

0 (0)

19 (79.2)

3 (12.5)

2 (8.3)

0 (0)

0 (0)

24 (100)

vacAs2/m2

1 (3.7)

22 (81.5)

2 (7.4)

2 (7.4)

0 (0)

0 (0)

27 (100)

  1. *Significant (P < 0.05)