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Table 6 Direct and indirect annual costs per patient related to IBS-C

From: Economic burden of moderate to severe irritable bowel syndrome with constipation in six European countries

  FRANCE GERMANY ITALY SPAIN SWEDEN UK
N 59 102 112 112 36 104
Direct cost to HS (€)
 Mean 1366.8 1422.6 937.1 1067.3 1276.9 2108.0
  (95% CI) (504.1, 2565.4) (621.2, 2600.9) (524.8, 1528.1) (729.6, 1446.6) (491.5, 2368.6) (1504.1, 2775.5)
 Min, Max 19.0–24,079.0 0.0, 47,390.0 0.0, 25,363.0 0.0, 9680.0 0.0, 13,937.7 45.7, 16,773.7
 Median 186.0 93.5 107.0 262.5 271.3 870.0
Direct cost to Patient (€)
 Mean 236.8 539.0 484.5 567.6 347.1 379.1
  (95% CI) (161.7, 332.9) (313.4, 840.9) (371.6, 627.2) (333.1, 840.7) (243.7, 484.0) (221.6, 579.6)
 Min, Max 14.0, 2358.0 0.0, 11,506.0 17.0, 6179.0 0.0, 8092.0 0.0, 1716.0 0.0, 6500.7
 Median 147.0 129.0 303.0 103.5 209.6 63.7
TOTAL DIRECT COST (€)
 Mean 1603.7 1961.6 1421.7 1635.0 1623.9 2487.1
 (95% CI) (715.4, 2815.7) (1063.0, 3142.0) (947.1, 2090.0) (1226.0, 2061.4) (803.4, 2710.9) (1848.2, 3150.3)
 Min-Max 33.0, 24,097.0 0.0, 48,403.0 17.0, 28,355.0 0.0, 10,782.0 29.5, 14,100.0 57.7, 16,780.9
 Median 342.0 340.0 489.0 518.5 634.8 1070.8
Indirect cost (€)1
 Mean 2473.8 2619.0 339.0 1361.9 11,248.5 4097.2
  (95% CI) (831.9, 4594.1) (1400.2, 4130.6) (182.4, 517.1) (312.5, 2866.4) (4580.2, 20,192.6) (2498.7, 5984.4)
 Min, Max 0.0, 37,753.0 0.0, 50,997.0 0.0, 5232.0 0.0, 59,630.0 0.0, 101,827.3 0.0, 45,271.7
 Median 0.0 0.0 0.0 0.0 442.8 156.3
  1. Currency conversion performed on 11th Feb 2014 (EUR/SEK = 8.8183; EUR/GBP = 0.8316). 1France N = 57
  2. HS Healthcare system
  3. Bold data are summation of Direct costs to HS + Direct costs to patient