Table 5 Univariate logistic regressions of health related quality of life variables for abnormal categorical liver function variables
From: The association of liver function and quality of life of patients with liver cancer
Variable Name | Child’s classes B to C | ALBI grades 2 to 3 | Presence of ascites | MELD grades 2 to 3 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | p-value | OR | 95% CI | p-value | OR | 95% CI | p-value | OR | 95% CI | p-value | |
EORTC QLQ-C30 | ||||||||||||
 Physical functioning | 0.972 | 0.964–0.981 | < 0.001 | 0.962 | 0.952–0.973 | < 0.001 | 0.974 | 0.965–0.982 | < 0.001 | 0.989 | 0.981–0.997 | 0.009 |
 Role functioning | 0.982 | 0.976–0.987 | < 0.001 | 0.975 | 0.967–0.983 | < 0.001 | 0.982 | 0.976–0.988 | < 0.001 | 0.992 | 0.986–0.998 | 0.007 |
 Emotional functioning | 0.997 | 0.990–1.005 | 0.508 | 0.997 | 0.989–1.004 | 0.396 | 0.995 | 0.988–1.003 | 0.262 | 1.002 | 0.994–1.010 | 0.597 |
 Cognitive functioning | 0.988 | 0.980–0.996 | 0.002 | 0.987 | 0.979–0.996 | 0.003 | 0.991 | 0.980–1.001 | 0.082 | 0.993 | 0.985–1.000 | 0.064 |
 Social functioning | 0.990 | 0.984–0.996 | 0.002 | 0.986 | 0.979–0.993 | < 0.001 | 0.989 | 0.982–0.996 | 0.001 | 0.995 | 0.989–1.001 | 0.124 |
 Global quality of life | 0.980 | 0.972–0.987 | < 0.001 | 0.978 | 0.970–0.986 | < 0.001 | 0.979 | 0.970–0.987 | < 0.001 | 0.989 | 0.981–0.996 | 0.003 |
 Fatigue | 1.022 | 1.015–1.029 | < 0.001 | 1.025 | 1.017–1.033 | < 0.001 | 1.025 | 1.017–1.032 | < 0.001 | 1.010 | 1.003–1.016 | 0.003 |
 Nausea & vomiting | 1.014 | 1.005–1.023 | 0.002 | 1.019 | 1.007–1.031 | 0.001 | 1.013 | 1.004–1.022 | 0.004 | 1.009 | 1.001–1.018 | 0.037 |
 Pain | 1.005 | 0.999–1.011 | 0.099 | 1.008 | 1.002–1.015 | 0.010 | 1.007 | 1.000–1.013 | 0.036 | 0.998 | 0.992–1.004 | 0.479 |
 Dyspnoea | 1.016 | 1.009–1.022 | < 0.001 | 1.016 | 1.009–1.023 | < 0.001 | 1.017 | 1.010–1.024 | < 0.001 | 1.007 | 1.001–1.013 | 0.033 |
 Insomnia | 1.009 | 1.004–1.015 | 0.001 | 1.010 | 1.005–1.016 | < 0.001 | 1.010 | 1.005–1.016 | 0.001 | 0.999 | 0.993–1.004 | 0.638 |
 Appetite loss | 1.014 | 1.008–1.019 | < 0.001 | 1.016 | 1.010–1.023 | < 0.001 | 1.015 | 1.009–1.020 | < 0.001 | 1.007 | 1.002–1.012 | 0.010 |
 Constipation | 1.004 | 0.998–1.011 | 0.205 | 1.002 | 0.995–1.010 | 0.508 | 1.007 | 0.999–1.014 | 0.072 | 0.998 | 0.991–1.005 | 0.586 |
 Diarrhea | 1.017 | 1.009–1.024 | < 0.001 | 1.016 | 1.007–1.025 | 0.003 | 1.017 | 1.010–1.025 | < 0.001 | 1.012 | 1.005–1.019 | 0.001 |
 Financial difficulties | 1.003 | 0.998–1.008 | 0.253 | 1.007 | 1.002–1.012 | 0.011 | 1.004 | 0.998–1.009 | 0.200 | 1.000 | 0.995–1.006 | 0.861 |
EORTC QLQ-HCC18 | ||||||||||||
 Fatigue | 1.024 | 1.016–1.032 | < 0.001 | 1.030 | 1.020–1.040 | < 0.001 | 1.022 | 1.013–1.030 | < 0.001 | 1.008 | 1.001–1.016 | 0.027 |
 Body Image | 1.029 | 1.020–1.038 | < 0.001 | 1.025 | 1.015–1.035 | < 0.001 | 1.034 | 1.024–1.044 | < 0.001 | 1.014 | 1.005–1.022 | 0.001 |
 Jaundice | 1.024 | 1.015–1.033 | < 0.001 | 1.011 | 1.002–1.021 | 0.020 | 1.016 | 1.007–1.025 | 0.001 | 1.018 | 1.009–1.027 | < 0.0001 |
 Nutrition | 1.027 | 1.017–1.037 | < 0.001 | 1.026 | 1.015–1.037 | < 0.001 | 1.024 | 1.014–1.033 | < 0.001 | 1.013 | 1.004–1.022 | 0.003 |
 Pain | 1.012 | 1.004–1.020 | 0.003 | 1.013 | 1.004–1.022 | 0.004 | 1.013 | 1.005–1.022 | 0.001 | 1.001 | 0.993–1.009 | 0.802 |
 Fever | 1.023 | 1.009–1.037 | 0.001 | 1.033 | 1.014–1.053 | 0.001 | 1.012 | 0.999–1.026 | 0.079 | 1.011 | 0.998–1.025 | 0.085 |
 Sex life | 1.004 | 0.999–1.010 | 0.130 | 1.007 | 1.001–1.013 | 0.017 | 1.002 | 0.997–1.008 | 0.431 | 1.005 | 0.999–1.010 | 0.089 |
 Abdominal swelling | 1.023 | 1.017–1.029 | < 0.001 | 1.019 | 1.012–1.026 | < 0.001 | 1.028 | 1.022–1.035 | < 0.001 | 1.009 | 1.004–1.015 | 0.001 |
Index-scores | ||||||||||||
 C30 index-score | 1.029 | 1.019–1.040 | < 0.001 | 1.037 | 1.024–1.049 | < 0.001 | 1.031 | 1.020–1.042 | < 0.001 | 1.011 | 1.001–1.021 | 0.028 |
 HCC18 index-score | 1.045 | 1.032–1.058 | < 0.001 | 1.044 | 1.029–1.058 | < 0.001 | 1.043 | 1.030–1.056 | < 0.001 | 1.020 | 1.009–1.032 | < 0.001 |