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Table 6 Factors associated with quality of life before and after diagnosis – 2015 survey

From: The impact of diagnosis on health-related quality of life in people with coeliac disease: a UK population-based longitudinal perspective

 

Before diagnosisa

After diagnosisb

Covariates

Coeff.

95% CI

p-value

Coeff.

95% CI

p-value

Male

0.01

(−0.04, 0.05)

0.728

0.01

(−0.02,0.04)

0.400

Age at diagnosis

 Less than 18

reference

  

reference

  

 18–34

0.03

(−0.04, 0.10)

0.412

−0.01

(− 0.06, 0.03)

0.632

 35–44

0.03

(−0.04, 0.10)

0.449

−0.02

(−0.07, 0.02)

0.333

 45–54

0.08

(0.01, 0.14)

0.022

0.003

(−0.04, 0.05)

0.903

 55–64

0.08

(0.01, 0.15)

0.022

−0.01

(−0.06, 0.03)

0.558

 65+

0.17

(0.09, 0.24)

< 0.001

0.02

(−0.03, 0.06)

0.537

No. of symptoms c

 None

reference

  

reference

  

 1–3 symptoms

−0.17

(−0.30, − 0.05)

0.007

− 0.05

(− 0.09, − 0.02)

0.003

 4+ more symptoms

−0.40

(− 0.52, − 0.27)

< 0.001

−0.17

(− 0.22, − 0.13)

< 0.001

Max symptoms duration

–

–

–

−0.002

(− 0.004, 0.0004)

0.104

No. of comorbidities

 None

–

–

–

reference

  

 1 comorbidity

–

–

–

−0.02

(−0.05, 0.01)

0.158

 2 comorbidities

–

–

–

− 0.03

(− 0.07, 0.003)

0.070

 3+ comorbidities

–

–

–

− 0.08

(−0.12, − 0.04)

< 0.001

Incomed < £20,000

−0.06

(− 0.10, − 0.02)

0.008

−0.07

(− 0.10, − 0.04)

< 0.001

Adherence to a GF diet

 All of the time

–

–

–

reference

  

 Most of the time

–

–

–

− 0.04

(− 0.08, 0.003)

0.067

 Some/little/none of the time

–

–

–

− 0.14

(−0.31, 0.03)

0.101

Access to GF products in shops

 Very easily

–

–

–

reference

  

 Fairly easily

–

–

–

−0.02

(−0.05, 0.004)

0.105

 Not easily

–

–

–

−0.07

(− 0.11, − 0.02)

0.007

Travel patterns AD

 The same

–

–

–

reference

  

 More likely to travel

–

–

–

−0.08

(− 0.15, − 0.01)

0.028

 Less likely to travel

–

–

–

−0.04

(− 0.07, 0.01)

0.002

Regiond

 North East

−0.01

(−0.12, 0.10)

0.813

−0.04

(− 0.11, 0.03)

0.317

 North West

0.03

(−0.05, 0.10)

0.471

−0.03

(−0.07, 0.02)

0.253

 Yorkshire and The Humber

0.02

(−0.05, 0.09)

0.599

−0.01

(−0.05, 0.04)

0.808

 East Midlands

0.003

(−0.07, 0.08)

0.927

-0.004

(−0.05, 0.04)

0.866

 West Midlands

−0.05

(−0.14, 0.03)

0.207

−0.04

(− 0.10, 0.01)

0.095

 East

−0.01

(−0.08, 0.06)

0.842

−0.01

(− 0.06, 0.03)

0.577

 London

−0.09

(−0.18, 0.01)

0.079

−0.02

(− 0.08, 0.04)

0.511

 South East

reference

  

reference

  

 South West

−0.01

(−0.08, 0.07)

0.872

−0.04

(−0.09, 0.01)

0.096

 Northern Ireland

−0.04

(−0.15, 0.07)

0.494

−0.04

(− 0.11, 0.03)

0.319

 Scotland

−0.03

(−0.11, 0.04)

0.422

−0.06

(− 0.11, − 0.01)

0.020

 Wales

0.04

(−0.05, 0.14)

0.370

−0.001

(− 0.06, 0.06)

0.971

  1. a Sample size: 1076; b Sample size: 1007; c Including CD-associated medical conditions dThe income and geographical variables both refer to the time of the survey and, therefore, before diagnosis, they can only be considered as a proxy for socioeconomic status and geographical location