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Table 6 Factors associated with quality of life before and after diagnosis – 2015 survey

From: The impact of diagnosis on health-related quality of life in people with coeliac disease: a UK population-based longitudinal perspective

  Before diagnosisa After diagnosisb
Covariates Coeff. 95% CI p-value Coeff. 95% CI p-value
Male 0.01 (−0.04, 0.05) 0.728 0.01 (−0.02,0.04) 0.400
Age at diagnosis
 Less than 18 reference    reference   
 18–34 0.03 (−0.04, 0.10) 0.412 −0.01 (− 0.06, 0.03) 0.632
 35–44 0.03 (−0.04, 0.10) 0.449 −0.02 (−0.07, 0.02) 0.333
 45–54 0.08 (0.01, 0.14) 0.022 0.003 (−0.04, 0.05) 0.903
 55–64 0.08 (0.01, 0.15) 0.022 −0.01 (−0.06, 0.03) 0.558
 65+ 0.17 (0.09, 0.24) < 0.001 0.02 (−0.03, 0.06) 0.537
No. of symptoms c
 None reference    reference   
 1–3 symptoms −0.17 (−0.30, − 0.05) 0.007 − 0.05 (− 0.09, − 0.02) 0.003
 4+ more symptoms −0.40 (− 0.52, − 0.27) < 0.001 −0.17 (− 0.22, − 0.13) < 0.001
Max symptoms duration −0.002 (− 0.004, 0.0004) 0.104
No. of comorbidities
 None reference   
 1 comorbidity −0.02 (−0.05, 0.01) 0.158
 2 comorbidities − 0.03 (− 0.07, 0.003) 0.070
 3+ comorbidities − 0.08 (−0.12, − 0.04) < 0.001
Incomed < £20,000 −0.06 (− 0.10, − 0.02) 0.008 −0.07 (− 0.10, − 0.04) < 0.001
Adherence to a GF diet
 All of the time reference   
 Most of the time − 0.04 (− 0.08, 0.003) 0.067
 Some/little/none of the time − 0.14 (−0.31, 0.03) 0.101
Access to GF products in shops
 Very easily reference   
 Fairly easily −0.02 (−0.05, 0.004) 0.105
 Not easily −0.07 (− 0.11, − 0.02) 0.007
Travel patterns AD
 The same reference   
 More likely to travel −0.08 (− 0.15, − 0.01) 0.028
 Less likely to travel −0.04 (− 0.07, 0.01) 0.002
Regiond
 North East −0.01 (−0.12, 0.10) 0.813 −0.04 (− 0.11, 0.03) 0.317
 North West 0.03 (−0.05, 0.10) 0.471 −0.03 (−0.07, 0.02) 0.253
 Yorkshire and The Humber 0.02 (−0.05, 0.09) 0.599 −0.01 (−0.05, 0.04) 0.808
 East Midlands 0.003 (−0.07, 0.08) 0.927 -0.004 (−0.05, 0.04) 0.866
 West Midlands −0.05 (−0.14, 0.03) 0.207 −0.04 (− 0.10, 0.01) 0.095
 East −0.01 (−0.08, 0.06) 0.842 −0.01 (− 0.06, 0.03) 0.577
 London −0.09 (−0.18, 0.01) 0.079 −0.02 (− 0.08, 0.04) 0.511
 South East reference    reference   
 South West −0.01 (−0.08, 0.07) 0.872 −0.04 (−0.09, 0.01) 0.096
 Northern Ireland −0.04 (−0.15, 0.07) 0.494 −0.04 (− 0.11, 0.03) 0.319
 Scotland −0.03 (−0.11, 0.04) 0.422 −0.06 (− 0.11, − 0.01) 0.020
 Wales 0.04 (−0.05, 0.14) 0.370 −0.001 (− 0.06, 0.06) 0.971
  1. a Sample size: 1076; b Sample size: 1007; c Including CD-associated medical conditions dThe income and geographical variables both refer to the time of the survey and, therefore, before diagnosis, they can only be considered as a proxy for socioeconomic status and geographical location