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Table 4 Respondents’ self-reported health on EQ-5D before diagnosis and at the survey time, 2006 and 2015

From: The impact of diagnosis on health-related quality of life in people with coeliac disease: a UK population-based longitudinal perspective

EQ-5D Question

2015

2006

Level 1 No problem

Level 2 Some problems

Level 3 Severe problems

Level 1 No problem

Level 2 Some problems

Level 3 Severe problems

N

%

N

%

N

%

N

%

N

%

N

%

Mobility

 Before diagnosis

1126

83.4

209

15.5

15

1.1

524

75.2

159

22.8

14

2.0

 After diagnosis

1169

86.6**

179

13.3*

2

0.2***

602

86.4***

93

13.3***

2

0.3**

 UK pop. norma

 

73.1

 

26.7

 

0.2

 

78

 

22

 

0

Self-care

 Before diagnosis

1295

95.9

48

3.6

7

0.5

648

93.0

35

5.0

14

2.0

 After diagnosis

1305

96.7

40

3.0

5

0.4

673

96.6**

18

2.6**

6

0.9*

 UK pop. norma

 

90.0

 

6.5

 

0.5

 

93

 

6

 

0

Usual activities

 Before diagnosis

899

66.6

395

29.3

56

4.2

403

57.8

249

35.7

45

6.5

 After diagnosis

1132

83.9***

198

14.7***

20

1.5***

574

82.4***

116

16.6***

7

1.0***

 UK pop. norma

 

75.9

 

21.5

 

2.6

 

78

 

19

 

3

Pain

 Before diagnosis

395

29.3

665

49.3

290

21.5

153

22.0

349

50.1

195

28.0

 After diagnosis

857

63.5***

445

33.0***

48

3.6***

416

59.7***

252

36.2***

29

4.2***

 UK pop. norma

 

54.6

 

41.3

 

6.2

 

58

 

37

 

4

Anxiety/depression

 Before diagnosis

837

62.0

411

30.4

102

7.6

351

50.4

259

37.2

87

12.5

 After diagnosis

1034

76.6***

285

21.1***

31

2.3***

518

74.3***

163

23.4***

16

2.3***

 UK pop. norma

 

73.1

 

24.8

 

2.2

 

75

 

23

 

2

  1. a UK population norms from Health Survey for England 2011 and 1996, respectively, standardised to age distribution of Coeliac UK survey respondents at the time of survey
  2. Proportion of respondents reporting significantly different level of response at the time of survey compared to before diagnosis: *** significant at the 1% level; **significant at the 5% level; *significant at the 10% level