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Table 2 Results of the meta-regression and subgroup analyses on shear wave elastography for differentiation of malignant and benign liver lesions

From: Diagnostic effect of shear wave elastography imaging for differentiation of malignant liver lesions: a meta-analysis

Covariates Subgroup No.of studies Pooled SEN
(95% CI)
P value Pooled SPE
(95% CI)
P value Meta-Regression Joint P Value
modality 1-pSWE 12 0.82(0.76–0.87) <0.01 0.83(0.77–0.89) 0.18 0.70
0-2D-SWE 3 0.84(0.75–0.93)   0.79(0.66–0.92)   
location 1-Asian 11 0.82(0.77–0.88) 0.02 0.82(0.76–0.89) 0.05 0.99
0- European or North America 4 0.82(0.72–0.92)   0.81(0.71–0.92)   
gold standard 1-histopathology 3 0.82(0.72–0.92) 0.02 0.85(0.73–0.96) 0.22 0.89
0- histopathology and/or other 12 0.82(0.77–0.88)   0.81(0.75–0.88)   
number of lesions 1- ≥ 100 10 0.84(0.79–0.88) 0.06 0.80(0.73–0.86) <0.01 0.10
0-<100 5 0.76(0.66–0.87)   0.88(0.80–0.97)   
prevalence of malignant lesions 1- ≥ 50% 11 0.84(0.79–0.88) 0.14 0.81(0.74–0.88) 0.02 0.29
0-<50% 4 0.75(0.63–0.87)   0.84(0.74–0.94)   
blinded 1-yes 11 0.82(0.77–0.88) 0.02 0.81(0.74–0.88) 0.02 0.79
0-unclear 4 0.82(0.72–0.92)   0.85(0.75–0.95)   
attrition rate 1- ≥ 10% 7 0.82(0.77–0.87) <0.01 0.81(0.74–0.88) 0.04 <0.01
0-<10% 4 0.80(0.75–0.86)   0.78(0.69–0.87)   
  1. SEN sensitivity, SPE specificity