Table 1 Main characteristics of the included studies
Author,year | Country | Elastography modality | Instrument | No.of patients | No.of liver lesions (Malignant) | Invalid measures(%) | Lesion types | Reference standard | Cut-off value (SWE/SWV ratio) |
|---|---|---|---|---|---|---|---|---|---|
Cho et al., 2010 [19] | Korea | pSWE | Siemens, ACUSON S2000 | 51 | 60(43) | 21.7% | HCC,CCC,LM,haemangioma | histopathology, CT/MRI | 2 m/s |
Davies et al., 2011 [21] | Holland | pSWE | Siemens, ACUSON S2000 | 37 | 45(10) | NR | haemangioma,LM | biopsy,CT/MRI | 2.5 m/s (1.6) |
Shuang-Ming et al., 2011 [20] | China | pSWE | Siemens, ACUSON S2000 | 116 | 128(68) | 22.7% | HCC, CCC,LM, haemangioma,FNH,RN,FFS,FFC,abscess,adenoma,SNN | histopathology, CT/MRI | 2.22 m/s |
Yu et al., 2011 [23] | Canada | pSWE | Siemens, ACUSON S2000 | 89 | 105(41) | 6.1% | HCC,LM,haemangioma,FNH,FFS,FFD,adenoma | biopsy, CT/MRI | 1.9 m/s |
Kapoor et al., 2011 [22] | India | pSWE | Siemens, ACUSON S2000 | 42 | 42(27) | 12.5% | HCC,LM,haemangiomas,lymphomas,FNH,sarcoid,abscesses,FFS | biopsy | 2.5 m/s |
Kim et al., 2013 [26] | Korea | pSWE | Siemens, ACUSON S2000 | 74 | 101(73) | NR | HCC,CCC,LM, hemangioma | pathology, CT/MRI | 2.73 m/s |
Park et al., 2013 [27] | Korea | pSWE | Siemens, ACUSON S2000 | 47 | 47(39) | 20% | HCC,CCC,LM,haemangioma,FNH | histopathology, CT/MRI | 1.82 m/s |
Zhang et al., 2014 [28] | China | pSWE | Siemens, ACUSON S2000 | 156 | 170(112) | 9.7% | HCC,CCC,LM,hemangioma,FNH,RN | histopathology, CT/MRI,DSA | 2.16 m/s |
Guo et al., 2015 [25] | China | pSWE | Siemens, ACUSON S2000 | 134 | 134(55) | 11.0% | HCC,CCC,LM,hemangioma,focal fatty degeneration,FFS,FNH, abscess | pathology, CT/MRI | 2.13 m/s (1.37) |
Lu et al., 2015 [24] | China | pSWE(Elast PQ) | Philips iu22 | 259 | 259(201) | 1.2% | HCC,ICC,LM,hemangioma, FNH, CN | histopathology | 13Kpa (1.3) |
Wu et al., 2016 [29] | China | pSWE | Siemens, ACUSON S2000 | 46 | 55(27) | NR | HCC,LM,hemangioma,FFS,RN | pathology, CEUS, CT/MRI | 2.22 m/s |
Dong et al., 2017 [30] | China | pSWE(ElastPQ) | Philips EPIQ7 | 154 | 154(129) | NR | HCC,ICC,CHC,sarcoma,LM,AML,FNH,hemangioma,IPT | histopathology | 2.06 m/s (1.67) |
Wen-Shuo et al., 2016 [31] | China | 2D-SWE(SuperSonic Imagine) | Aixplorer | 221 | 229(164) | 6.6% | HCC,ICC,CHC,LM,sarcomaneuroendocrine cancer,Unclassified cancer,FNH,hemangioma,angioleiomyolipoma,cavernous vascular tumor,abscess,Inflammatory pseudo-tumor,inflammation,solitary fibroma | histopathology,CEUS | Emax39.60Kpa/ Emean24.43 Kpa |
Gerber et al., 2017 [32] | Germany | 2D-SWE(SuperSonic Imagine) | Aixplorer | 106 | 106(64) | 24.3% | haemangioma,FNH, adenoma,FFS, RN,cholangiofibroma, HCC,CCC, LM | histopathology,CEUS, CT/MRI | Emean20.7 Kpa |
Grgurevic et al., 2018 [33] | Switzerland | 2D-SWE(SuperSonic Imagine) | Aixplorer | 196 | 259(168) | 26.3% | HCC,CCC,LM,haemangioma, FNH | biopsy, CT/MRI | Emean22.3 Kpa |