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Table 1 Main characteristics of the included studies

From: Diagnostic effect of shear wave elastography imaging for differentiation of malignant liver lesions: a meta-analysis

Author,year Country Elastography modality Instrument No.of patients No.of liver lesions (Malignant) Invalid measures(%) Lesion types Reference standard Cut-off value (SWE/SWV ratio)
Cho et al., 2010 [19] Korea pSWE Siemens, ACUSON S2000 51 60(43) 21.7% HCC,CCC,LM,haemangioma histopathology, CT/MRI 2 m/s
Davies et al., 2011 [21] Holland pSWE Siemens, ACUSON S2000 37 45(10) NR haemangioma,LM biopsy,CT/MRI 2.5 m/s (1.6)
Shuang-Ming et al., 2011 [20] China pSWE Siemens, ACUSON S2000 116 128(68) 22.7% HCC, CCC,LM, haemangioma,FNH,RN,FFS,FFC,abscess,adenoma,SNN histopathology, CT/MRI 2.22 m/s
Yu et al., 2011 [23] Canada pSWE Siemens, ACUSON S2000 89 105(41) 6.1% HCC,LM,haemangioma,FNH,FFS,FFD,adenoma biopsy, CT/MRI 1.9 m/s
Kapoor et al., 2011 [22] India pSWE Siemens, ACUSON S2000 42 42(27) 12.5% HCC,LM,haemangiomas,lymphomas,FNH,sarcoid,abscesses,FFS biopsy 2.5 m/s
Kim et al., 2013 [26] Korea pSWE Siemens, ACUSON S2000 74 101(73) NR HCC,CCC,LM, hemangioma pathology, CT/MRI 2.73 m/s
Park et al., 2013 [27] Korea pSWE Siemens, ACUSON S2000 47 47(39) 20% HCC,CCC,LM,haemangioma,FNH histopathology, CT/MRI 1.82 m/s
Zhang et al., 2014 [28] China pSWE Siemens, ACUSON S2000 156 170(112) 9.7% HCC,CCC,LM,hemangioma,FNH,RN histopathology, CT/MRI,DSA 2.16 m/s
Guo et al., 2015 [25] China pSWE Siemens, ACUSON S2000 134 134(55) 11.0% HCC,CCC,LM,hemangioma,focal fatty degeneration,FFS,FNH, abscess pathology, CT/MRI 2.13 m/s (1.37)
Lu et al., 2015 [24] China pSWE(Elast PQ) Philips iu22 259 259(201) 1.2% HCC,ICC,LM,hemangioma, FNH, CN histopathology 13Kpa (1.3)
Wu et al., 2016 [29] China pSWE Siemens, ACUSON S2000 46 55(27) NR HCC,LM,hemangioma,FFS,RN pathology, CEUS, CT/MRI 2.22 m/s
Dong et al., 2017 [30] China pSWE(ElastPQ) Philips EPIQ7 154 154(129) NR HCC,ICC,CHC,sarcoma,LM,AML,FNH,hemangioma,IPT histopathology 2.06 m/s (1.67)
Wen-Shuo et al., 2016 [31] China 2D-SWE(SuperSonic Imagine) Aixplorer 221 229(164) 6.6% HCC,ICC,CHC,LM,sarcomaneuroendocrine cancer,Unclassified cancer,FNH,hemangioma,angioleiomyolipoma,cavernous vascular tumor,abscess,Inflammatory pseudo-tumor,inflammation,solitary fibroma histopathology,CEUS Emax39.60Kpa/
Emean24.43 Kpa
Gerber et al., 2017 [32] Germany 2D-SWE(SuperSonic Imagine) Aixplorer 106 106(64) 24.3% haemangioma,FNH, adenoma,FFS, RN,cholangiofibroma, HCC,CCC, LM histopathology,CEUS, CT/MRI Emean20.7 Kpa
Grgurevic et al., 2018 [33] Switzerland 2D-SWE(SuperSonic Imagine) Aixplorer 196 259(168) 26.3% HCC,CCC,LM,haemangioma, FNH biopsy, CT/MRI Emean22.3 Kpa
  1. No number, HCC hepatocellular carcinoma, ICC intrahepatic cholangiocellular carcinoma, CCC cholangiocarcinoma, CHC Combined hepatocellular carcinoma and intrahepatic cholangiocarcinoma, LMN liver metastasis, FNH focal nodular hyperplasia, FFS focal fatty sparing/ nodule of focal fatty sparing, FFD focal fat deposits, FFC focal fatty change, SNN solitary necrotic nodule, RN regenerative node, CN cirrhotic nodule, AML hepatic angiomyolipoma, IPT inflammatory pseudotumor, CT computer tomography, MRI magnetic resonance imaging, CEUS contrast enhanced ultrasound, MRI; DSA digital subtraction angiography, NR not reported