Table 1 Summary of cases of post-colectomy enteritis reported after 2008
From: A literature review and case report of severe and refractory post-colectomy enteritis
No. | Sex | Age | Age at UC Dx | Extent of UC | Backwash ileitis | Serology | Surgery type | Onset of enteritis | Extent of enteritis | Infx | Induction therapy | Maintenance therapy | Remission | Procedure | FU |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 (this) | F | 51 | 49 | Pancolitis | No | pANCA+, ASCA- | 1st sub-TAC + ileostomy, 2nd IPAA | 4 mo | D, I, P | No | HC 50 mg q6 h → MP 30 mg qd iv | AZA (1.3 mg/kg/d) | AP | Closure of ileostomy | 19 mo |
2 [7] | M | 23 | 17 | Pancolitis | Yes | pANCA+, ASCA- | 1st TAC + ileostomy, 2nd IPAA | 3 mo | S, D, I, P | No | MP 40 mg qd iv (improved in 24 h) | AZA (3 mg/kg/d) | SS | Closure of ileostomy scheduled | 10 mo |
3 [7] | F | 29 | 21 | Pancolitis | No | ND | 1st TAC + ileostomy, 2nd IPAA | 4 mo | S, D, I, P | No | MP 40 mg qd iv (improved in 24 h) | AZA + allopurinol→certolizumab+MTX, P 10–20 mg | SD | NM | 57 mo |
4 [7] | M | 30 | 2 | Pancolitis | NM | pANCA+, ASCA- | TAC + IPAA | 27 mo | S, D, I, P | No | MP 40 mg qd iv (improved in 24 h) | AZA (2 mg/kg/d) | SS | NM | 43 mo |
5 [7] | M | 57 | 48 | Pancolitis | No | pANCA+, ASCA- | TAC + ileostomy | 27 mo | S, D, I | No | MP 40 mg qd iv (improved in 24 h) | AZA (2.2 mg/kg/d) | SS | NM | 6 mo |
6 [13] | F | 43 | 37 | Pancolitis | No | ANCA-, ASCA- | TAC + ileostomy | 3 mo | S, D, I | No | MP 20 mg bid iv (did not improve) | Tacrolimus (po 3 mg bid, 4–8 ng/ml) | Since tacrolimus | NA | 6 mo |
7 [5] | M | 56 | 46 | Pancolitis | No | ND | TAC + IPAA | 4 mo | D, I, P | No | HC 100 mg q6 h (improved in 48 h) | AZA (125 mg/d → stop | SS | NM | 48 mo |
8 [6] | F | 56 | 44 | Left-side | No | ND | Proctocolectomy+ileostomy | 26 days | D, I, P | No | P 20 mg qd po → MP 20 mg tid iv | NA | Death | NA | Death |
9 [14] | F | 47 | 43 | Pancolitis | NM | ND | colectomy+ ileostomy | 4 mo | D, J | No | Corticosteroids (dose unknown) | Tacrolimus (po 3 mg bid) | SS | NM | NM |
10 [11] | M | 19 | 17 | Pancolitis | NM | ND | proctocolectomy+IPAA | 12 days | S, D, I | CMV | P 0.6 mg/kg/day po | IFX 5 mg/kg | AP | 2nd op due to perforation | 4 mo |
11 [9] | F | 25 | 25 | 21 | Pancolitis | Yes | NM | 9 days | D, J, I, P | No | P 40 mg qd po → DEX 8 mg qd | NA | SS | NM | NM |