Table 2 Median AST, ALT, PLT, APRI, and FIB-4 values at different time points in different subgroups of patients with and without SVR12

55 (36–87)

27 (21–36)^***

25 (20–35)^***

25 (20–33)^***

27 (21–34)^***

66 (41–102)

25 (17–35)^***

22 (16–33)^***

21 (16–30)^***

22 (16–29)^***

142 (99–190)

152 (108–202)^***

163 (110–205)^***

158 (106–202)^***

151 (109–195)^***

1.19 (0.62–2.44)

0.50 (0.32–0.95)^***

0.51 (0.31–0.92)^***

0.48 (0.31–0.88)^***

0.52 (0.33–0.92)^***

2.88 (1.56–5.60)

2.10 (1.30–3.65)^***

2.15 (1.30–3.65)^***

2.11 (1.37–3.76)^***

2.22 (1.45–3.82)^***

68 (46–113)

32 (25–41)^***

31 (24–41)^***

29 (23–37)^***

31 (25–39)^***

78 (48–123)

28 (21–41)^***

25 (19–37)^***

24 (18–34)^***

25 (19–35)^***

100 (78–126)

112 (83–136)^***

113 (87–137)^***

110 (86–140)^***

111 (84–131)^***

2.12 (1.26–3.83)

0.87 (0.64–1.38)^***

0.79 (0.56–1.32)^***

0.79 (0.55–1.21)^***

0.83 (0.59–1.33)^***

5.34 (3.69–7.79)

3.58 (2.47–5.21)^***

3.47 (2.55–5.15)^***

3.56 (2.33–4.94)^***

3.61 (2.59–5.12)^***

40 (30–60)

22 (19–28)^***

21 (18–27)^***

21 (18–27)^***

22 (19–28)^***

54 (35–81)

20 (16–29)^***

18 (14–27)^***

18 (14–27)^***

18 (14–26)^***

192 (167–226)

204 (178–238)^**

205 (177–241)^***

206 (176–236)^***

195 (171–226)

0.61 (0.42–0.94)

0.32 (0.25–0.43)^***

0.31 (0.23–0.42)^***

0.31 (0.24–0.42)^***

0.33 (0.26–0.44)^***

1.55 (1.10–2.13)

1.30 (1.00–1.66)^***

1.30 (0.94–1.70)^***

1.37 (1.02–1.81)^***

1.44 (1.06–1.85)^***

46 (34–217)

31 (19–59)^*

29 (20–53)^*

36 (19–55)^*

40 (27–163)

58 (31–143)

28 (14–45)^*

18 (14–39)^*

31 (15–49)^*

42 (16–153)

87 (50–198)

99 (52–197)

130 (74–197)

95 (45–166)

99 (63–170)

2.71 (0.44–7.47)

0.84 (0.27–2.62)^*

0.82 (0.28–2.30)^*

1.42 (0.33–2.91)^*

1.87 (0.43–6.86)^*

5.92 (1.89–14.48)

4.20 (1.69–9.00)^*

4.54 (1.74–8.71)

4.52 (2.16–9.94)

4.80 (2.36–14.05)