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Table 2 Clinical parameters of NHANES III Participants Aged 60 and over by NAFLD status, U.S. 1988–1994

From: Prevalence and long-term outcomes of non-alcoholic fatty liver disease among elderly individuals from the United States

 

Aged 60–74 (n = 2095)

Aged 75 and over (n = 1176)

All (n = 3271)

NAFLD

No NAFLD

NAFLD

No NAFLD

AST (IU/L), mean (SE)

21.75 (0.27)*

19.98 (0.17)

21.28 (0.47)

20.51 (0.17)

20.73 (0.13)

ALT (IU/L), mean (SE)

17.83 (0.39)*†

12.43 (0.25)

14.26 (0.61)*

10.68 (0.20)

13.89 (0.29)

Albumin (g/dL), mean (SE)

4.04 (0.02)

4.02 (0.02)

3.99 (0.01)

3.98 (0.01)

4.02 (0.01)

Platelet (1000 cell/uL), mean (SE)

259.01 (3.75)

261.57 (2.90)

252.90 (2.84)

247.93 (3.39)

257.51 (2.23)

ASCVD, mean (SE)

20.80 (0.32)*†

14.42 (0.26)

44.39 (0.63)*

40.95 (0.66)

24.21 (0.42)

eGFR, mean (SE)

76.20 (0.38)*†

78.40 (0.48)

61.34 (0.96)*

65.79 (0.70)

73.67 (0.33)

HOMA, mean (SE)

7.36 (0.36)*

1.79 (0.03)

7.24 (0.57)*

1.80 (0.02)

4.01 (0.14)

NFS, mean (SE)

−0.64 (0.06)*†

−1.06 (0.05)

0.07 (0.06)

−0.05 (0.05)

−0.64 (0.04)

NFS, %

 > 0.676

13.92 (1.08)*†

6.13 (0.80)

31.54 (2.05)*

23.49 (1.21)

14.20 (0.84)

 0.676 - -1.455

60.65 (1.86)

59.50 (1.29)

60.27 (2.14)*

65.78 (1.73)

61.00 (0.88)

 < −1.455

25.43 (2.07)*†

34.38 (1.47)

8.19 (1.11)

10.74 (1.20)

24.80 (1.01)

APRI, mean (SE)

0.28 (0.01)*

0.25 (0.00)

0.28 (0.01)

0.27 (0.00)

0.27 (0.00)

APRI (> 0.7) %

2.05 (0.36)*

0.56 (0.15)

1.77 (0.76)

1.08 (0.25)

1.22 (0.14)

  1. NAFLD was defined as a US FLI score of ≥ 30 in the absence of any other cause of chronic liver disease
  2. *Different from No NAFLD in the same age group (p < .05)
  3. †Different from NAFLD Aged 75 and over (p < .05)
  4. Data displayed by weighted percentage/mean (SE)
  5. Abbreviation: CI confidence interval, ASCVD atherosclerotic cardiovascular disease risk score, APRI aspartate aminotransferase to platelet ratio index, FIB-4 fibrosis-4 score, NFS NAFLD fibrosis score, eGFR estimated glomerular filtration rate mL/min/1.73 m2