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Table 3 Characteristics of included studies

From: Impact of primary colorectal Cancer location on the KRAS status and its prognostic value

Author

Year/country

Study design

LCC

RCC

LCC

RCC

wt

mut

wt

mut

HR(95%CI)

HR(95%CI)

Chiu JW

2018/Canada

P

65

46

36

37

Hou Y

2018/China

R

196

117

62

86

Natsume S

2018/Japan

R

327

97

98

53

0.58 (0.37–0.86)

Charlton ME

2017/USA

R

2849

2701

1.18 (1.05–1.3)

0.93 (0.83–1.03)

Gao XH

2017/China

P

42

30

27

16

Kim ST

2017/Korea

R

115

9

25

4

Chang YY

2016/China

P

425

221

221

187

Sasaki K

2016/USA

R

201

96

65

64

1.81 (1.11–2.96)

1.03 (0.51–2.08)

Sun P

2016/China

R

60

48

44

40

Kodaz H

2015/Turkey

R

80

72

13

12

Ye JX

2015/China

R

100

50

94

67

Tong JH

2014/China

R

680

461

156

209

von Einem JC

2014/Germany

P

68

32

27

19

1.3 (0.68–2.34)

0.63 (0.43–0.92)

Cushman- Vokoun AM

2013/USA

R

13

16

21

15

Zhu XL

2012/China

R

79

45

59

47

Abubaker J

2009/Saudi Arabia

R

79

62

26

18

Bleeker WA

2000/Netherlands

R

26

3

16

10

  1. LCC left-side colon cancer, RCC right-side colon cancer, wt KRAS wild type, mut KRAS mutant type, HR hazard ratio, CI confidence interval, P prospective, R retrospective