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Table 3 Characteristics of included studies

From: Impact of primary colorectal Cancer location on the KRAS status and its prognostic value

Author Year/country Study design LCC RCC LCC RCC
wt mut wt mut HR(95%CI) HR(95%CI)
Chiu JW 2018/Canada P 65 46 36 37
Hou Y 2018/China R 196 117 62 86
Natsume S 2018/Japan R 327 97 98 53 0.58 (0.37–0.86)
Charlton ME 2017/USA R 2849 2701 1.18 (1.05–1.3) 0.93 (0.83–1.03)
Gao XH 2017/China P 42 30 27 16
Kim ST 2017/Korea R 115 9 25 4
Chang YY 2016/China P 425 221 221 187
Sasaki K 2016/USA R 201 96 65 64 1.81 (1.11–2.96) 1.03 (0.51–2.08)
Sun P 2016/China R 60 48 44 40
Kodaz H 2015/Turkey R 80 72 13 12
Ye JX 2015/China R 100 50 94 67
Tong JH 2014/China R 680 461 156 209
von Einem JC 2014/Germany P 68 32 27 19 1.3 (0.68–2.34) 0.63 (0.43–0.92)
Cushman- Vokoun AM 2013/USA R 13 16 21 15
Zhu XL 2012/China R 79 45 59 47
Abubaker J 2009/Saudi Arabia R 79 62 26 18
Bleeker WA 2000/Netherlands R 26 3 16 10
  1. LCC left-side colon cancer, RCC right-side colon cancer, wt KRAS wild type, mut KRAS mutant type, HR hazard ratio, CI confidence interval, P prospective, R retrospective