Skip to main content

Table 4 Related factors for positive β2-GPI antibody in non-AIP CP patients

From: Autoantibody detection is not recommended for chronic pancreatitis: a cross-sectional Study of 557 patients

Predictors

Univariate Analysis

Multivariate Analysis

OR(95% CI)

P

OR(95% CI)

P

Female sex

1.042(0.509–2.130)

0.911

  

BMI, kg/m2

0.998(0.987–1.009)

0.751

  

Age at the onset of CP, ya

0.992(0.954–1.031)

0.684

  

Age at the diagnosis of CP, ya

1.028(0.986–1.071)

0.195

  

Etiology

 

0.812

  

 ACP

Control

  

 ICP

0.991(0.059–16.668)

0.995

  

 Abnormal anatomy of pancreatic duct

0.377(0.013–11.052)

0.571

  

 Hereditary CP

1.770(0.164–19.055)

0.638

  

 Post-traumatic CP

0(0)

0.999

  

Pancreatic stones

0.680(0.220–2.103)

0.503

  

Adolescent

1.167(0.318–4.284)

0.816

  

DM

2.315(1.174–4.566)

0.015

2.768(1.510–5.072)

0.001

Steatorrhea

1.462(0.705–3.033)

0.307

  

Common bile duct stricture

2.785(1.159–6.693)

0.022

2.952(1.343–6.489)

0.007

PPC

0.938(0.397–2.215)

0.883

  

SAP

0.906(0.160–5.139)

0.911

  

Onset manifestations

 

0.240

  

 Abdominal pain

Control

  

 Pancreatic insufficiency

1.081(0.414–2.821)

0.874

  

 Others

2.949(0.780–11.145)

0.111

  

Type of pain

 

0.879

  

 None

Control

  

 Repeat attacks of acute pancreatitis

1.131(0.292–4.377)

0.858

  

 Repeat pain

1.121(0.331–3.797)

0.854

  

 Repeat acute attacks and pain

1.132(0.245–5.243)

0.874

  

 Chronic pain

0.470(0.070–3.155)

0.437

  

Drinking history (g/d)

 

0.828

  

 0

Control

  

  < 20

0.488(0.056–4.282)

0.517

  

 20~80

0.649(0.209–2.138)

0.497

  

  > 80

0.634(0.043–9.452)

0.741

  

Smoking history, pack-year

 

0.445

  

 0

Control

  

  < 60

0.565(0.230–1.386)

0.213

  

  ≥ 60

0.533(0.058–4.928)

0.579

  

DM in first−/second−/third-degree relatives

0.272(0.076–0.076)

0.045

0.266(0.079–0.897)

0.033

Pancreatic diseases in first−/second−/third-degree relatives

0(0)

0.999

  

Elevated IgGb

1.639(0.409–6.564)

0.485

  

Elevated IgG4b

2.797(0.814–9.614)

0.103

  
  1. CP Chronic pancreatitis, ACP Alcoholic chronic pancreatitis, AIP Autoimmune pancreatitis; ICP Idiopathic chronic pancreatitis, DM Diabetes mellitus, PPC Pancreatic pseudocyst, SAP Severe acute pancreatitis
  2. aMean ± SD
  3. bSerum IgG and IgG4 were measured by immunoturbidimetry assay (Immage800 specific protein analyzer, Beckman, USA; BN2 specific protein analyzer, Siemens, Germany), and their upper limits were 15.6 g/l, 2.0 g/l respectively
Back to article page

BMC Gastroenterology

ISSN: 1471-230X

Contact us