Table 3 Related factors for positive β2-GPI antibody in non-AIP CP patients [n(%)]
Predictors | Positiven(n = 51) | Negetive(n = 506) | P |
|---|---|---|---|
Female sex | 15(29.4) | 149(29.4) | 0.996 |
BMI, kg/m2 | 21.49 ± 3.06a | 25.23 ± 93.39 | 0.775 |
Age at the onset of CP, ya | 40.31 ± 18.54a | 36.22 ± 16.36 | 0.093 |
Age at the diagnosis of CP, ya | 46.09 ± 15.33a | 41.07 ± 15.15 | 0.135 |
Etiology | 0.410 | ||
ACP | 6(11.8) | 106(20.9) | |
ICP | 41(80.4) | 351(69.4) | |
Abnormal anatomy of pancreatic duct | 1(2.0) | 28(5.5) | |
Hereditary CP | 3(5.9) | 19(3.8) | |
Post-traumatic CP | 0(0) | 2(0.4) | |
Pancreatic stones | 46(90.2) | 470(92.9) | 0.675 |
Adolescent | 5(9.8) | 67(13.2) | 0.486 |
DM | 22(43.1) | 113(22.3) | 0.001 |
Steatorrhea | 14(27.5) | 118(23.3) | 0.508 |
Common bile duct stricture | 11(19.6) | 37(7.3) | 0.006 |
PPC | 8(15.7) | 86(17.0) | 0.812 |
SAP | 2(3.9) | 15(3.0) | 1.000 |
Onset manifestations | 0.110 | ||
Abdominal pain | 35(68.6) | 401(79.2) | |
Pancreatic insufficiency | 10(19.6) | 78(15.4) | |
Others | 6(11.8) | 27(5.3) | |
Type of pain | 0.576 | ||
None | 7(13.7) | 50(9.9) | |
Repeat attacks of acute pancreatitis | 14(27.5) | 151(29.8) | |
Repeat pain | 21(41.2) | 174(34.4) | |
Repeat acute attacks and pain | 7(13.7) | 89(17.6) | |
Chronic pain | 2(3.9) | 42(8.3) | |
Drinking history (g/d) | 0.078 | ||
0 | 38(74.5) | 315(62.3) | |
< 20 | 1(2.0) | 17(3.4) | |
20~80 | 5(9.8) | 58(11.5) | |
> 80 | 7(13.7) | 116(22.9) | |
Smoking history, pack-year | 0.020 | ||
0 | 39(76.5) | 303(59.9) | |
< 60 | 11(21.6) | 182(36.0) | |
≥ 60 | 1(2.0) | 21(4.2) | |
DM in first−/second−/third-degree relatives | 3(5.9) | 82(16.2) | 0.051 |
Pancreatic diseases in first−/second−/third-degree relatives | 0(0) | 19(3.8) | 0.316 |
Elevated IgGb | 3(5.9) | 16(3.2) | 0.538 |
Elevated IgG4b | 5(9.8) | 16(3.2) | 0.047 |