Table 2 Comparison of positive rate of nine autoantibodies between non-AIP CP patients and historial healthy controls
Autoantibody | non-AIP CP patients | Historial Healthy controls | P | ||||
|---|---|---|---|---|---|---|---|
Positive | Negative | Frequency (%) | Positive | Negative | Frequency (%) | ||
Anti-β2-glycoprotein I antibody | 51 | 506 | 9.16 | 37 | 1839 | 1.97 | < 0.001 |
Anti-smooth muscle antibody | 17 | 540 | 3.05 | 24 | 302 | 7.36 | 0.003 |
Anticardiolipin antibody | 16 | 541 | 2.87 | 93 | 1431 | 6.10 | 0.003 |
Anti-mitochondrial antibody | 9 | 548 | 1.62 | 14 | 1340 | 1.03 | 0.224 |
Anti SS-B antibody | 9 | 548 | 1.62 | 4 | 1659 | 0.24 | < 0.001 |
Anti-double-stranded DNA antibody | 8 | 549 | 1.44 | 0 | 202 | 0 | 0.190 |
Anti-single-stranded DNA antibody | 6 | 551 | 1.08 | 14 | 568 | 2.41 | 0.088 |
Anti-histone antibody | 5 | 552 | 0.90 | 14 | 711 | 1.93 | 0.129 |
Anti-ribonucleoprotein antibody | 3 | 554 | 0.54 | 13 | 1078 | 1.19 | 0.201 |
Anti-proteinase 3 IgG antibody | 3 | 554 | 0.54 | 0 | 237 | 0 | 0.558 |
Anti-PM-Scl antibody | 2 | 555 | 0.36 | – | – | – | – |
Anti-neutrophil cytoplasmic antibody | 2 | 555 | 0.36 | – | – | – | – |
Anti-ribosomal antibody | 2 | 555 | 0.36 | – | – | – | – |
Anti SS-A antibody | 1 | 556 | 0.18 | – | – | – | – |
Anti-Jo-1 antibody | 1 | 556 | 0.18 | – | – | – | – |
Anti-SM antibody | 1 | 556 | 0.18 | – | – | – | – |
Anti-myeloperoxidase antibody | 1 | 556 | 0.18 | – | – | – | – |
anti-neutrophil perinuclear antibody | 1 | 556 | 0.18 | – | – | – | – |
Anti-proliferating cell nuclear antigen antibody | 1 | 556 | 0.18 | – | – | – | – |
Anti-Scl 70 antibody | 0 | 556 | 0 | – | – | – | – |
Anti-nucleosome antibodies | 0 | 556 | 0 | – | – | – | – |
Anti-glomerular basement membrane antibody | 0 | 556 | 0 | – | – | – | – |