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Table 1 Clinical characteristics of 557 non-AIP CP patients

From: Autoantibody detection is not recommended for chronic pancreatitis: a cross-sectional Study of 557 patients

Items

Male (n = 393)

n(%)

Female (n = 164)

n(%)

Overall (n = 557)

n(%)

Body mass index, kg/m2a

26.56 ± 105.94

20.89 ± 3.58

24.89 ± 89.01

Age at the onset of CP, ya

38.89 ± 15.86

31.09 ± 17.05

36.60 ± 16.59

Age at the diagnosis of CP, ya

43.60 ± 14.40

36.57 ± 16.00

41.53 ± 15.22

Etiology

 ACP

97(24.7)

15(9.1)

112(20.1)

 ICP

266(67.7)

126(76.8)

392(70.4)

 Abnormal anatomy of pancreatic duct

18(4.6)

11(6.7)

29(5.2)

 Hereditary CP

11(2.8)

11(6.7)

22(3.9)

 Post-traumatic CP

1(0.3)

1(0.6)

2(0.4)

Pancreatic stones

363(92.4)

153(93.3)

517(92.6)

Adolescent

40(10.2)

32(19.5)

72(12.9)

DM

102(26.0)

33(20.1)

135(24.2)

Steatorrhea

91(23.2)

41(25.0)

132(23.7)

Common bile duct stricture

40(10.2)

7(14.9)

47(8.4)

PPC

74(18.8)

20(12.2)

94(16.9)

SAP

13(3.3)

4(2.4)

17(3.0)

Onset manifestations

 Abdominal pain

320(81.4)

116(70.7)

436(78.3)

 Pancreatic insufficiency

53(13.5)

35(21.3)

88(15.8)

 Others

20(5.1)

13(7.9)

33(5.9)

Type of abdominal pain

 None

31(7.9)

26(15.9)

57(10.2)

 Repeat attacks of acute pancreatitis

120(30.5)

45(27.4)

165(29.6)

 Repeat pain

138(35.1)

57(34.8)

195(35.0)

 Repeat acute attacks and pain

71(18.1)

25(15.2)

96(17.2)

 Chronic pain

33(8.4)

11(6.7)

44(7.9)

Drinking history (g/d)

 0

223(56.7)

130(79.3)

353(63.4)

 < 20

13(3.3)

5(3.0)

18(3.2)

 20~80

53(13.5)

10(6.1)

63(11.3)

 > 80

104(26.5)

19(11.6)

123(22.1)b

Smoking history, pack-year

 0

212(53.9)

130(79.3)

342(61.4)

 < 60

161(41.0)

32(19.5)

193(34.6)

 ≥ 60

20(5.1)

2(1.2)

22(3.9)

DM in first−/second−/third-degree relatives

57(14.5)

28(17.1)

85(15.3)

Pancreatic diseases in first−/second−/third-degree relatives

12(3.1)

7(4.3)

19(3.4)

Elevated IgGc

16(4.1)

3(1.8)

19(3.4)

Elevated IgG4c

19(4.8)

2(1.2)

21(3.8)

  1. CP Chronic pancreatitis, ACP Alcoholic chronic pancreatitis, AIP Autoimmune pancreatitis, ICP Idiopathic chronic pancreatitis, DM Diabetes mellitus, PPC Pancreatic pseudocyst, SAP Severe acute pancreatitis
  2. aMean ± SD
  3. b123 patients with drinking history > 80 g/d included 112 cases with ACP, 7 cases with hereditary CP, 3 cases with anatomical abnormality and one case with post-traumatic CP
  4. cSerum IgG and IgG4 were measured by immunoturbidimetry assay (Immage800 specific protein analyzer, Beckman, USA; BN2 specific protein analyzer, Siemens, Germany), and their upper limits were 15.6 g/l and 2.0 g/l respectively