Table 2 Molecular alterations in small bowel carcinomas in our cohort
N° | BRCA | TP53 | ERBB2 | KRAS | MSI | PIK3CA | KEAP1 |
|---|---|---|---|---|---|---|---|
1 | BRCA2 p.N986Ifs*5 | p.R273C | wt | wt | MSI | wt | p.Y490C |
2 | wt | p.C135Y | wt | p.G12D | n.a. | wt | wt |
3 | BRCA1 p.V1234Qfs*8 | p.C275Y | wt | wt | MSS | wt | wt |
4 | BRCA1 p.E1540* | wt | wt | wt | MSS | wt | p.R320L |
5 | wt | p.G245S | p.T862A | wt | MSS | wt | wt |
6 | wt | wt | wt | p.G12 V | MSS | p.E545G | wt |
7 | BRCA1 p.T77 M BRCA2 p.R1512C | wt | wt | p.A146T | MSI Lynch-syndrome | p.E542K | p.R202H |
8 | wt | p.R175H | wt | p.G12 V | MSS | wt | wt |
9 | wt | wt. | wt. | p.G12C | MSS | wt | wt |
10 | wt | p.R248Q | wt. | wt | MSS | p.E542K | wt |
11 | wt | wt | wt | wt | MSS | wt | wt |