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Table 5 Genetic variations detected in in the study cohorts

From: The frequency, clinical course, and health related quality of life in adults with Gilbert’s syndrome: a longitudinal study

Gene polymorphism Allele status Total Individuals with recurrent episodes of overt jaundice (GS: n = 83) Individuals with GS and eradicated HCV (n = 18) Control subjects (n = 100)
UGT1A1*6
 SNP 211G > A; (n,%) −/− 189 80 (96.386) 12 (66.667) 97 (97)
*6/− 10 2 (2.409) 5 (27.778) 3 (3)
*6/*6 1 0 1 (5.555) 0
UGT1A1*27
 SNP 686C > A; (n,%) −/− 199 81 (97.59) 18 (100) 100 (100)
*27/− 2 2(2.409) 0 0
*27/*27 0 0 0 0
UGT1A1*28
 TA repeat A(TA)7TAA; (n,%) −/− 100 0 0 100
*28/− 3 2 (2.409) 1(5.555) 0
*28/*28 98 81(97.59) 17 (94.444) 0
UGT1A1*60
 SNP -3263 T > A −/− 189 71 13 95
*60/− 13 5 3 5
*60/*60 9 7 2 0
  1. GS Gilbert syndrome, HCV hepatitis C virus infection, UGT1A1 Uridine diphosphoglucuronate-glucuronosyltransferase A1 SNPs ingle nucleotide polymorphism
  2. * Allele designation