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Fig. 2 | BMC Gastroenterology

Fig. 2

From: Role of colonic microbiota in the pathogenesis of ulcerative colitis

Fig. 2

Diversity analysis of the microbiota. a. Comparison of the relative abundance of bacteria in three layers at genus level between groups. The microbial composition within the luminal content, inner layer and outer mucus layer of SPF mice was determined by 16S amplicon analysis. Representative bar graphs from control and model groups are shown. b. Comparison of alpha diversity index (good_coverage index) between groups. c. Comparison of luminal contents flora beta diversity index between groups (Unifrac weighted distance PCoA and Anosim analysis). d. Comparison of outer mucus layer flora beta diversity index between groups (Unifrac weighted distance PCoA and Anosim analysis). e. The comparison of inner mucus layer flora beta diversity index between groups (Unifrac weighted distance PCoA and Anosim analysis). Principle coordinates analysis (PCoA) on weighted UniFrac distances was performed on all operational taxonomic units. The closer the samples are to one another the more similar the bacterial diversity and richness are. P-values to determine the statistical significance of clustering were calculated using the Anosim method. *CC: the luminal content of control group. CO: the outer mucus layer of the control group. CI: the inner mucus layer of the control group. MC: the luminal content of the model group. MO: the outer mucus layer of the model group. MI: the inner mucus layer of the model group

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