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Fig. 2 | BMC Gastroenterology

Fig. 2

From: Mitochondrial neurogastrointestinal encephalopathy: a clinicopathological mimic of Crohn’s disease

Fig. 2

Colonoscopic image, colonic histology, and MRI brain for Patient 2 (A-F). (a) Colonoscopy showing aphthous ulceration in the descending colon. (b) Colonic biopsy showing patchy increase in chronic inflammatory cells within the lamina propria and focal cryptitis, H&E stain, magnification × 40. (c) Colonic biopsy showing multiple, round and refractile eosinophilic cytoplasmic inclusions of megalomitochondria within the submucosal ganglionic cells, H&E stain, magnification × 400. (d) Axial brain TSE MRI for Patient 2 with white matter changes, as described for Patient 1 Fig. 1f and g

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