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Table 2 Classification of Papanicolaou Society for assessment of cytological sampling of the pancreatobiliary system. (NET - neuroendocrine tumor; IPMN - intraductal papillary mucinous neoplasm; MCN - mucinous cystic neoplasm)

From: Prospective comparison of slow-pull and standard suction techniques of endoscopic ultrasound-guided fine needle aspiration in the diagnosis of solid pancreatic cancer

Papanicolaou society of cytopathology system for reporting pancreaticobiliary cytology

I. Non-diagnostic

 

II. Negative (for malignancy)

Benign pancreatic tissue

Acute, chronic or autoimmune pancreatitis

Pseudocyst, lymphoepithelial cyst

Splenule/accessory spleen

III. Atypical

 

IV. Neoplastic - Benign

Serous cystadenoma

Neuroendocrine microadenoma

Lymphangioma

IV. Neoplastic - Other

Well-differentiated NET

IPMN, all grades of dysplasia

MCN, all grades of dysplasia

Solid-pseudopapillary neoplasm

V. Suspicious (for malignancy)

 

VI. Positive or Malignant

Ductal adenocarcinoma of the pancreas and its variants

Cholangiocarcinoma

Acinar cell carcinoma

Poorly differentiated (small and large cell) NET

Pancreatoblastoma

Lymphoma

Metastatic malignancy