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Table 2 Relationship between atypia grades and histological subtypes of differentiated-type EGC [3, 4, 8]

From: Endoscopic and clinicopathological features of intramucosal, histologically mixed-type, low-grade, well-differentiated gastric tubular adenocarcinoma with the potential for late-onset lymph node metastasis

Atypia grade

Histological subtype

Remarks

Tub1

Tub2

Low-grade (LG)

LG-tub1

LG-tub2

Tumours that are diagnosed as LG-tub1 by Japanese gastrointestinal pathologists may be

High-grade (HG)

HG-tub1

HG-tub2

diagnosed as high-grade dysplasia by Western gastrointestinal pathologists [7].

  1. EGC early gastric cancer; LG-tub1 low-grade, well-differentiated tubular adenocarcinoma; LG-tub2 low-grade, moderately differentiated tubular adeno-carcinoma; HG-tub1 high-grade, well-differentiated tubular adenocarcinoma; HG-tub2 high-grade, moderately differentiated tubular adenocarcinoma