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Table 2 Prognostic factors for DFS and DSS in patients with SPNP according to cox regression models

From: Prognostic value of progesterone receptor in solid pseudopapillary neoplasm of the pancreas: evaluation of a pooled case series

 

Univariate COX model

Multivariate COX model

Prognostic factors

β

Hazard ratio (95%CI)

P value

β

Hazard ratio (95%CI)

P value

DFS (n = 280)

 Age (≥40 y)

0.982

2.67 (1.10–6.48)

0.030

0.536

1.71 (0.38–7.79)

0.872

 Gender (male)

−0.615

0.54 (0.18–1.59)

0.265

   

 Location (Head/Neck)

0.399

1.49 (0.64–3.45)

0.351

   

 Tumor size (≥7 cm)

0.809

2.25 (0.87–5.77)

0.093

   

 *Ki67 (≥5%)

1.770

5.87 (1.65–20.95)

0.006

0.2 93

1.34 (0.19–9.68)

0.771

 *PR negative)

2.962

19.34 (5.08–73.61)

< 0.001

2.674

14.50 (1.98–106.05)

0.008

DSS (n = 280)

 Age (≥40 y)

0.454

1.58 (0.41–6.09)

0.511

   

 Gender (male)

−1.295

0.27 (0.07–1.06)

0.061

   

 Location (Head/Neck)

−0.067

0.94 (0.27–3.23)

0.916

   

 Tumor size (≥7 cm)

1.878

6.54 (1.39–30.82)

0.018

1.7 16

5.56 (0.60–51.19)

0.130

 *Ki67 (≥5%)

1.214

3.37 (0.65–17.48)

0.149

   

 *PR (negative)

2.800

16.45 (3.66–73.87)

< 0.001

2.2 13

9.15 (1.89–44.17)

0.006

  1. *Number of SPN patients with Ki67 and PR results are 82 and 83 respectively