Table 1 SNP analysis of human cytokines and IL-4Rα
SNPa | Cytokine (Promoter/coding sequence) | Restriction enzyme | Genotypes (band size) | ||
|---|---|---|---|---|---|
Wild homozygous | Heterozygous | Homozygous for mutation | |||
- 592 (A/C) | IL-10 | RSA I | 175 and 237 bpb | 412, 175 and 237 bp | 412 bp |
- 819 (T/C) | IL-10 | Mae III | 209 bp | 209, 125 and 84 bp | 125 and 84 bp |
- 1082(G/A) | IL-10 | Mnl I | 139 bp | 139, 106 and 33 bp | 106 and 33 bp |
.- 590 (C/T) | IL-4 | BsmFI (FaqI) | 192 and 60 bp | 252, 192 and 60 bp | 252 bp |
Ile50Val | IL-4Rα | RsaI | 273 bp | 273, 254 and 19 bp | 254 and 19 bp |
Q576R | IL-4Rα | MspI | 107 and 16 bp | 107, 89, 18 and 16 bp | 89, 18 and 16 bp |