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Table 3 The predictive discrimination ability of the nomogram compared to the MELD, CTP, and SOFA score systems in the primary and validation cohorts

From: Development and external validation of a prognostic nomogram for acute decompensation of chronic hepatitis B cirrhosis

  C-index 95% CI for C-index Goodness of Fit Comparison of models
Lower Upper LR R2 Dxy SD Z P value
Primary cohort (n = 509)
 MELDs 0.820 0.764 0.878 72.07 0.185 −0.343 0.083 −4.12 < 0.001
 CTPs 0.793 0.744 0.842 70.79 0.175 −0.687 0.051 −13.5 < 0.001
 SOFAs 0.868 0.829 0.907 119.46 0.282 −0.398 0.075 −5.33 < 0.001
 CLIF-C ADs 0.716 0.636 0.796 45.36 0.121 −0.476 0.078 −6.10 < 0.001
 Nomogram 0.897 0.850 0.943 165.63 0.374  
Validation cohort (n = 620)
 MELDs 0.826 0.794 0.857 238.69 0.336 0.451 0.045 10.13 < 0.001
 CTPs 0.741 0.707 0.776 130.11 0.196 −0.557 0.035 −15.94 < 0.001
 SOFAs 0.837 0.807 0.866 255.24 0.349 −0.215 0.049 −4.39 < 0.001
 CLIF-C ADs 0.569 0.525 0.615 8.47 0.015 −0.501 0.041 −12.22 < 0.001
 Nomogram 0.839 0.811 0.867 268.38 0.363