| ALE- | ALE+ | p-value* |
---|---|---|---|
 | n = 1810 | n = 349 |  |
Age (years) | 49 (41–56) | 47 (40–55) | 0.03 |
Male sex | 812 (44.9%) | 267 (76.5%) | < 0.001 |
Weight (kg) | 72.0 (61.0–82.0) | 84.0 (74.0–95.0) | < 0.001 |
Height (m) | 1.68 (1.60–1.74) | 1.73 (1.67–1.79) | < 0.001 |
BMI (kg/m2) | 25.1 (22.6–28.1) | 27.9 (25.4–30.9) | < 0.001 |
BMI class (NIH) |  |  | < 0.001 |
 Underweight | 19 (1.0%) | 0 (0.0%) |  |
 Normal | 871 (48.1%) | 66 (18.9%) |  |
 Overweight | 607 (33.5%) | 170 (48.7%) |  |
 Obesity class 1 | 230 (12.7%) | 81 (23.2%) |  |
 Obesity class 2 | 65 (3.6%) | 28 (8.0%) |  |
 Obesity class 3 | 18 (1.0%) | 4 (1.1%) |  |
Fatty liver | 637 (35.2%) | 259 (74.2%) | < 0.001 |
Fatty liver degree |  |  | < 0.001 |
 Light | 428 (67.2%) | 107 (41.3%) |  |
 Moderate | 151 (23.7%) | 102 (39.4%) |  |
 Severe | 58 (9.1%) | 50 (19.3%) |  |
Fatty liver type |  |  | < 0.001 |
 None | 1173 (64.8%) | 90 (25.8%) |  |
 NAFLD | 407 (22.5%) | 160 (45.8%) |  |
 AFLD | 230 (12.7%) | 99 (28.4%) |  |
Waist circumference (cm) | 100.0 (93.0–107.0) | 105.0 (100.0–113.0) | < 0.001 |
Large waist circumference | 1236 (68.3%) | 259 (74.2%) | 0.028 |
Glucose (mg/dl) | 89 (83–96) | 93 (87–102) | < 0.001 |
High fasting glucose | 307 (17.0%) | 109 (31.2%) | < 0.001 |
Triglycerides (mg/dl) | 97 (68–139) | 138 (98–206) | < 0.001 |
High triglycerides | 405 (22.4%) | 159 (45.6%) | < 0.001 |
Total cholesterol (mg/dl) | 207 (184–234) | 215 (192–240) | 0.005 |
HDL cholesterol (mg/dl) | 61 (51–73) | 50 (44–61) | < 0.001 |
Low HDL | 219 (12.1%) | 64 (18.3%) | 0.002 |
LDL cholesterol (mg/dl) | 126 (104–150) | 138 (117–159) | < 0.001 |
Systolic blood pressure (mm Hg) | 125 (120–140) | 130 (120–140) | < 0.001 |
Diastolic blood pressure (mm Hg) | 80 (80–90) | 85 (80–90) | < 0.001 |
High blood pressure | 1053 (58.2%) | 270 (77.4%) | < 0.001 |
Metabolic syndrome | 444 (24.5%) | 171 (49.0%) | < 0.001 |
Metabolic syndrome score |  |  | < 0.001 |
 0 | 216 (11.9%) | 19 (5.4%) |  |
 1 | 595 (32.9%) | 59 (16.9%) |  |
 2 | 555 (30.7%) | 100 (28.7%) |  |
 3 | 294 (16.2%) | 97 (27.8%) |  |
 4 | 117 (6.5%) | 59 (16.9%) |  |
 5 | 33 (1.8%) | 15 (4.3%) |  |
ALT (U/l) | 20 (15–26) | 50 (44–63) | < 0.001 |
AST (U/l) | 20 (18–24) | 33 (29–41) | < 0.001 |
GGT (U/l) | 17 (12–26) | 42 (27–69) | < 0.001 |
Total bilirubin (mg/dl) | 0.60 (0.40–0.81) | 0.62 (0.49–0.90) | 0.003 |
Alcohol intake (alcohol units/day) | 2 (0–4) | 3 (1–5) | < 0.001 |
Wine intake (alcohol units/day) | 2 (0–2) | 2 (1–3) | < 0.001 |
Beer intake (alcohol units/day) | 0 (0–1) | 0 (0–1) | 0.52 |
Liquor intake (alcohol units/day) | 0 (0–0) | 0 (0–1) | < 0.001 |