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Fig. 2 | BMC Gastroenterology

Fig. 2

From: Neuroprotective effects of vitamin D on high fat diet- and palmitic acid-induced enteric neuronal loss in mice

Fig. 2

Effects of PA, VD and 7DHC in primary cultures of enteric neurons. a, c Supplementation with 1α,25-hydroxy-vitamin D3 (VD, 10-11-10-7M) or 7-dihydrocholesterol (7DHC 10-11-10-7M) had no effect on neuronal survival. b Cultures treated with palmitic acid (PA, 4x10-4M) induced enteric neuronal loss, supplementation with VD but not 7DHC prevented the PA induced loss. Untreated controls were run in parallel. Data presented as mean ± SEM, per treatment group, control n=6-12 per group, palmitic acid (PA) n=6, VD n=6-12, 7DHC, PA (4x10-4M) + VD (10-11-10-7M) n=6, PA (4x10-4M) +7DHC (10-9-10-7M) n=6, ** p<0.01

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BMC Gastroenterology

ISSN: 1471-230X

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