Skip to main content

Table 1 General Characteristics of 2153 patients with CP

From: Risk factor for steatorrhea in pediatric chronic pancreatitis patients

Items

Overall (n = 2153)

n (%)

Pediatrics (n = 291)

n (%)

Adults (n = 1862)

n (%)

P value

Gender (male)

1486 (69.0%)

143 (49.1%)

1343 (72.1%)

< 0.001

Age at the onset of CP, ya

38.230 ± 16.606

11.622 ± 4.652

42.388 ± 13.692

< 0.001

Age at the diagnosis of CP, ya

43.077 ± 15.548

19.727 ± 8.953

46.727 ± 12.980

< 0.001

Smoking history

723 (33.6%)

16 (5.5%)

707 (38.0%)

< 0.001

Alcohol consumption

–

–

–

< 0.001

 0 g/d

1426 (66.2%)

272 (93.5%)

1154 (62.0%)

–

 0-20 g/d

70 (3.3%)

8 (2.7%)

62 (3.3%)

–

 20-80 g/d

237 (11.0%)

8 (2.7%)

229 (12.3%)

–

  > 80 g/d

420 (19.5%)

3 (1.0%)

417 (22.4%)

–

Body mass indexa

20.894 ± 3.354

19.380 ± 3.362

24.696 ± 88.765

0.338

Etiology

–

–

–

< 0.001

 ICP

1633 (75.8%)

248 (85.2%)

1385 (74.4%)

–

 ACP

404 (18.8%)

2 (0.7%)

402 (21.6%)

–

 Abnormal anatomy of pancreatic duct

64 (3.0%)

24 (8.2%)

40 (2.1%)

–

 HCP

30 (1.4%)

12 (4.1%)

18 (1.0%)

–

 Post-traumatic CP

10 (0.5%)

3 (1.0%)

7 (0.4%)

–

 Hyperlipidemic CP

12 (0.6%)

2 (0.7%)

10 (0.5%)

–

Initial manifestations

–

–

–

< 0.001

 Abdominal pain

1796 (83.4%)

280 (96.2%)

1516 (81.4%)

–

 Endocrine/Exocrine dysfunction

218 (10.1%)

9 (3.1%)

209 (11.2%)

–

 Others

139 (6.5%)

2 (0.7%)

137 (7.4%)

–

Pancreatic stonesb

1627 (75.6%)

269 (92.4%)

1358 (72.9%)

< 0.001

 Age at pancreatic stones diagnosis

41.415 ± 15.323

20.443 ± 8.547

45.569 ± 12.746

< 0.001

 Time between onset and pancreatic stone

5.762 ± 7.144

8.829 ± 9.174

5.154 ± 6.504

< 0.001

DM

616 (28.6%)

38 (13.1%)

578 (31.0%)

< 0.001

 Age at DM diagnosisa

45.848 ± 11.812

28.578 ± 11.965

46.984 ± 10.890

< 0.001

 Time between onset and DMa

5.136 ± 7.276

16.617 ± 13.447

4.381 ± 5.964

< 0.001

Steatorrhea

493 (22.9%)

46 (15.8%)

447 (24.0%)

0.002

 Age at steatorrhea diagnosisa

42.563 ± 12.555

25.880 ± 9.358

44.279 ± 11.549

< 0.001

 Time between onset and steatorrheaa

5.245 ± 8.485

13.929 ± 10.562

4.351 ± 7.719

< 0.001

Pancreatic pseudocyst

350 (16.3%)

30 (10.3%)

320 (17.2%)

0.003

 Age at pancreatic pseudocyst diagnosisa

45.776 ± 15.077

16.232 ± 7.210

48.589 ± 12.365

< 0.001

 Time between onset and pancreatic pseudocysta

4.989 ± 6.954

5.640 ± 5.828

4.927 ± 7.058

0.605

Biliary stricture

340 (15.8%)

19 (6.5%)

321 (17.2%)

< 0.001

 Age at biliary stricture diagnosisa

51.218 ± 13.169

31.548 ± 13.686

52.382 ± 12.200

< 0.001

 Time between onset and biliary stricturea

5.592 ± 8.637

21.197 ± 17.565

4.668 ± 6.809

0.001

Pancreatic cancer

21 (1.0%)

1 (0.3%)

20 (1.1%)

0.238

Death

70 (3.3%)

2 (0.7%)

68 (3.7%)

0.008

Morphology of MPD

–

–

–

< 0.001

 Pancreatic stone alone

590 (27.4%)

95 (32.6%)

495 (26.6%)

–

 MPD stenosis alone

598 (27.8%)

57 (19.6%)

541 (29.1%)

–

 MPD stenosis and stone

728 (33.8%)

128 (44.0%)

600 (32.2%)

–

 Complex pathologic changes

237 (11.0%)

11 (3.8%)

226 (12.1%)

–

Type of pain

–

–

–

< 0.001

 Recurrent acute pancreatitis

681 (31.6%)

102 (35.1%)

579 (31.3%)

–

 Recurrent pain

638 (29.6%)

65 (22.3%)

573 (30.8%)

–

 Recurrent acute pancreatitis and pain

570 (26.5%)

106 (36.4%)

464 (24.9%)

–

 Chronic pain

106 (4.9%)

14 (4.8%)

92 (4.9%)

–

 Without pain

158 (7.3%)

4 (1.4%)

154 (8.3%)

–

Severe acute pancreatitis

66 (3.1%)

7 (2.4%)

59 (3.2%)

0.482

Pancreatic duct successful drainagec

1930 (89.6%)

255 (87.6%)

1675 (90.0%)

0.216

Overall treatment

–

–

–

< 0.001

 Endotherapy alone

1505 (69.9%)

247 (84.9%)

1258 (67.6%)

–

 Surgery alone

244 (11.3%)

10 (3.4%)

234 (12.6%)

–

 Both endotherapy and surgery

181 (8.4%)

20 (6.9%)

161 (8.6%)

–

 Conservative treatment

223 (10.4%)

14 (4.8%)

209 (11.2%)

–

DM in first−/second−/third-degree relatives

135 (6.3%)

38 (13.1%)

97 (5.2%)

< 0.001

Pancreatic diseases in first−/second−/third-degree relatives (excluding hereditary CP)

37 (1.7%)

15 (5.2%)

22 (1.2%)

< 0.001

  1. CP chronic pancreatitis, DM diabetes mellitus, ICP idiopathic chronic pancreatitis, ACP alcoholic chronic pancreatitis, HCP hereditary chronic pancreatitis, MPD main pancreatic duct
  2. aMean ± SD
  3. bPancreatic calcifications were also regarded as stones that are located in branch pancreatic duct or ductulus
  4. cPatients with successful MPD drainage are those whose CP was established after ERCP or pancreatic surgery or those who underwent successful MPD drainage during administration when CP diagnosis was established