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Table 2 Univariate and multivariate linear regression analysis for MELD score

From: Macrocytic anemia is associated with the severity of liver impairment in patients with hepatitis B virus-related decompensated cirrhosis: a retrospective cross-sectional study

Variable Univariate Multivariate
β (CI 95%) P value β (CI 95%) P value
Age 0.05(−0.02,0.13) 0.160 0.07(0.01,0.15) 0.028
Male 2.25(1.15,3.36) < 0.001 1.49(0.29,2.70) 0.015
Smoking 1.93(0.82,3.03) < 0.001 0.21(−1.03,1.44) 0.742
Drinking 1.59(0.34,2.85) 0.013 0.73(−0.56,2.01) 0.269
Diabetes 0.53(− 1.11,2.16) 0.527   
Hypertension 0.15(−1.53,1.84) 0.857   
Hemoglobin, g/L
 > 90 Ref   
 60–90 1.09(−0.21,2.39) 0.100   
 < 60 −1.35(−3.90,1.20) 0.298   
Total cholesterol −2.77(−3.37,-2.16) < 0.001 −2.53(− 3.14,-1.93) < 0.001
Systolic blood pressure −0.01(− 0.04,0.03) 0.863   
Diastolic blood pressure −0.01(− 0.06,0.05) 0.900   
Anemia classification
 Normocytic anemia Ref Ref
 Macrocytic anemia 2.80(1.59,4.01) < 0.001 1.94(0.81,3.07) < 0.001
 Microcytic anemia −1.73(−3.72,0.27) 0.089 − 1.77(− 3.59,0.05) 0.057
  1. MELD model for end stage liver disease, β estimated coefficient, 95% CI 95% confidence interval