Identification of risk factors for pancreatic pseudocysts formation, intervention and recurrence: a 15-year retrospective analysis in a tertiary hospital in China

Table 2 Univariate and multivariate regression analyses of risk factors associated with PPC which needs intervention

Variable	Univiarite analysis			Multivariate analysis
Variable	Group C (n = 347)	Group D (n = 412)	P-value	OR (95% CI)	P-value
Age (years)	46.85 ± 15.19	48.04 ± 14.27	0.264
Sex (male/female)	193/154	242/170	0.387
BMI	24.59 ± 4.62	24.13 ± 4.83	0.614
Smoking (yes/no)	115/232	137/275	0.974
Comorbidity
Hypertension	32/315	46/366	0.380
Diabetes	39/308	44/368	0.806
Respiratory diseases	13/336	22/390	0.289
Liver diseases	14/333	20/392	0.586
Pancreatitis (acute/chronic)	285/62	369/43	0.003^a	4.782 (1.897-10.173)	0.038^a
Recurrent pancreatitis (yes/no)	68/279	75/337	0.625
Symptoms
Pain	341	407	0.554
Fever	48	64	0.510
Etiology
Biliary	149	205	0.061
Alcoholic	89	74	0.010^a	7.634 (2.125-13.558)	0.016^a
Trauma	18	24	0.701
Hyperglycemia	23	26	0.859
Post ERCP	37	47	0.745
Idiopathic	31	36	0.905
Lab examination
Amylase (U/L)	912.47 ± 674.63	819.23 ± 626.37	0.172
WBC (10⁹/L)	14.71 ± 8.65	13.85 ± 8.23	0.384
CRP (mg/L)	82.05 ± 28.39	88.72 ± 31.33	0.271
TBIL (umol/L)	56.42 ± 34.71	52.93 ± 38.37	0.325
Time from pancreatitis to pseudocyst (weeks)	8.47 ± 1.78	9.12 ± 2.05	0.311
Location			0.043^a	2.534 (0.892-3.665)	0.083
Head	129	183
Body/Tail	218	229
Number			0.037^a	2.754 (0.821-4.378)	0.064
Single	183	186
Multiple	164	226
Size			0.011^a	8.834 (2.017-16.649)	0.002^a
≥ 6 cm	144	134
< 6 cm	203	278
IPN	44	34	0.045^a	1.811 (0.893-3.552)	0.056
Antibiotics (Yes/No)	302/45	342/70	0.124
Somatostatin (Yes/No)	331/16	394/18	0.872

ISSN: 1471-230X