Quantifying the effects of aging and urbanization on major gastrointestinal diseases to guide preventative strategies

Table 4 Mortality risk from major gastrointestinal diseases with urbanization and aging

Diseases	Effect of region			Effect of age			Age*Region
Diseases	B	Confidence interval(95%)	p	B	Confidence interval(95%)	p	B	Confidence interval(95%)	p
Diarrhea	−5.760	−7.723~ − 3.797	< 0.001	1.511	1.329~ 1.693	< 0.001	2.065	− 0.059~ 4.190	0.057
Hepatitis B	−1.274	−1.487~ − 1.060	< 0.001	1.983	1.839~ 2.129	< 0.001	− 0.127	− 0.427~ 0.174	0.409
Hepatitis C	0.720	−0.977~ 2.418	0.405	2.105	0.145~ 4.065	0.035	0.858	−1.399~ 3.116	0.456
Esophagus Ca.	−0.662	− 0.841~ − 0.510	< 0.001	2.966	2.861~ 3.071	< 0.001	− 0.073	− 0.251~ 0.104	0.417
Stomach Ca.	−0.559	−0.660~ − 0.458	< 0.001	2.822	2.748~ 2.895	< 0.001	0.115	−0.004~ 0.234	0.058
Colon/rectum Ca.	0.296	0.140~ 0.452	< 0.001	2.662	2.515~ 2.809	< 0.001	0.425	0.238~ 0.613	< 0.001
Liver Ca.	−0.438	− 0.514~ − 0.362	< 0.001	2.027	1.958~ 2.095	< 0.001	0.220	0.117~ 0.323	< 0.001
Pancreas Ca.	1.216	0.936~ 1.495	< 0.001	2.303	1.972~ 2.633	< 0.001	0.629	0.263~ 0.994	0.001
Diabetes	0.095	−0.080~ 0.271	0.287	3.015	2.866~ 3.165	< 0.001	0.635	0.436~ 0.834	< 0.001
Ulcer	−1.870	−2.236~ − 1.504	< 0.001	3.166	3.013~ 3.320	< 0.001	0.165	−0.241~ 0.571	0.425
Liver cirrhosis	−0.733	−0.872~ − 0.595	< 0.001	2.171	2.062~ 2.280	< 0.001	− 0.314	−0.507~ − 0.122	0.001
Appendicitis	−3.490	−5.480~ − 1.501	0.001	2.689	2.226~ 3.153	< 0.001	1.680	−0.450~ 3.810	0.122

ISSN: 1471-230X