Fig. 3
Pathologic findings. a Diaminobenzidine staining of liver specimens revealed focal necrosis of the liver surrounded by fibrous tissue. The focal necrosis area revealed infiltration by lymphocytes, plasma cells and eosinophils. Peripheral hepatocytes were partially silt. b Immunoglobulin G (IgG) immunohistochemical staining showing increased numbers of IgG-positive plasma cells in the liver lesions (30–60/ high power field [HPF], × 400). c Diaminobenzidine staining of pancreas tissues revealed focal areas of glandular atrophy accompanied by lymphocyte, plasma cell and eosinophil infiltration and fibrous tissue hyperplasia. d IgG immunohistochemical staining showing increased numbers of IgG-positive plasma cells in the pancreas (30–80/HPF, × 400). e Diaminobenzidine staining of gallbladder tissue revealed chronic cholecystitis, focal lymphoid hyperplasia, formation of lymph follicles and infiltration of the gallbladder wall by the lymphocytes, plasma cells and eosinophils. f IgG immunohistochemical staining showing increased numbers of IgG-positive plasma cells in the gallbladder (30–80/HPF, × 400). g Hematin and yepin staining of duodenum tissue revealed lymphocytic, plasmacytic and neutrophilic infiltration of the inner layer of the duodenal mucosa with congestion and dilatation of the blood vessels. h IgG immunohistochemical staining showing increased numbers of IgG-positive plasma cells in the duodenum (> 100 /HPF, × 400)