Table 1 EOPC and older PDAC demographics, past medical history, environmental and genetic risk factors
From: Demographic, clinical, and pathological features of early onset pancreatic cancer patients
Characteristics | EOPC (35), % (≤50 years) | PDAC (334), % (> 50 years) | p value |
|---|---|---|---|
Mean Age | 45.71 | 66.19 | Â |
(Range in years) | (33 to 50) | (51 to 85) | Â |
Gender | Â | Â | 0.043 |
 Male | 25 (71%) | 179 (54%) |  |
 Female | 10 (29%) | 155 (46%) |  |
Ethnicity | Â | Â | 0.002 |
 British | 13 (37%) | 233 (70%) |  |
 Asian | 5 (14%) | 9 (3%) |  |
 Black | 3 (9%) | 22 (7%) |  |
 Other white background | 4 (11%) | 11 (3%) |  |
 Any other group | 2 (6%) | 12 (4%) |  |
 Missing | 8 (23%) | 47 (14%) |  |
Smoking status | Â | Â | 0.850 |
 Current smoker | 7 (20%) | 55 (16%) |  |
 Ex-smoker | 4 (11%) | 45 (13%) |  |
 No | 13 (37%) | 109 (33%) |  |
 Missing | 11 (31%) | 125 (37%) |  |
History of alcohol excess | Â | Â | 0.556 |
 Yes | 9 (26%) | 69 (21%) |  |
 No | 14 (40%) | 140 (42%) |  |
 Missing | 12 (34%) | 125 (37%) |  |
Obesity | Â | Â | 0.244 |
 Yes | 2 (6%) | 23 (7%) |  |
 No | 8 (23%) | 37 (11%) |  |
 Missing | 25 (71%) | 274 (82%) |  |
Genetic syndrome | Â | Â | 0.989 |
 Yes | 1 (3%) | 9 (3%) |  |
 No | 30 (86%) | 266 (80%) |  |
 Missing | 4 (11%) | 59 (18%) |  |
History of chronic pancreatitis | Â | Â | 0.092 |
 Yes | 5 (14%) | 96 (29%) |  |
 No | 23 (66%) | 191 (57%) |  |
 Missing | 7 (20%) | 47 (14%) |  |
History of diabetes | Â | Â | 0.385 |
 Yes | 8 (23%) | 58 (17%) |  |
 No | 22 (63%) | 233 (70%) |  |
 Missing | 5 (14%) | 43 (13%) |  |
Allergya | Â | Â | 0.853 |
 Yes | 2 (6%) | 35 (10%) |  |
 No | 15 (43%) | 228 (68%) |  |
 Missing | 18 (51%) | 71 (21%) |  |
Previous radiotherapy | Â | Â | 0.838 |
 Yes | 1 (3%) | 14 (4%) |  |
 No | 23 (66%) | 261 (78%) |  |
 Missing | 11 (31%) | 59 (18%) |  |
Previous abdominal surgeryb | Â | Â | 0.056 |
 Yes | 9 (26%) | 78 (23%) |  |
 No | 9 (26%) | 194 (58%) |  |
 Missing | 17 (49%) | 62 (19%) |  |