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Table 1 EOPC and older PDAC demographics, past medical history, environmental and genetic risk factors

From: Demographic, clinical, and pathological features of early onset pancreatic cancer patients

Characteristics EOPC (35), % (≤50 years) PDAC (334), % (> 50 years) p value
Mean Age 45.71 66.19  
(Range in years) (33 to 50) (51 to 85)  
Gender    0.043
 Male 25 (71%) 179 (54%)  
 Female 10 (29%) 155 (46%)  
Ethnicity    0.002
 British 13 (37%) 233 (70%)  
 Asian 5 (14%) 9 (3%)  
 Black 3 (9%) 22 (7%)  
 Other white background 4 (11%) 11 (3%)  
 Any other group 2 (6%) 12 (4%)  
 Missing 8 (23%) 47 (14%)  
Smoking status    0.850
 Current smoker 7 (20%) 55 (16%)  
 Ex-smoker 4 (11%) 45 (13%)  
 No 13 (37%) 109 (33%)  
 Missing 11 (31%) 125 (37%)  
History of alcohol excess    0.556
 Yes 9 (26%) 69 (21%)  
 No 14 (40%) 140 (42%)  
 Missing 12 (34%) 125 (37%)  
Obesity    0.244
 Yes 2 (6%) 23 (7%)  
 No 8 (23%) 37 (11%)  
 Missing 25 (71%) 274 (82%)  
Genetic syndrome    0.989
 Yes 1 (3%) 9 (3%)  
 No 30 (86%) 266 (80%)  
 Missing 4 (11%) 59 (18%)  
History of chronic pancreatitis    0.092
 Yes 5 (14%) 96 (29%)  
 No 23 (66%) 191 (57%)  
 Missing 7 (20%) 47 (14%)  
History of diabetes    0.385
 Yes 8 (23%) 58 (17%)  
 No 22 (63%) 233 (70%)  
 Missing 5 (14%) 43 (13%)  
Allergya    0.853
 Yes 2 (6%) 35 (10%)  
 No 15 (43%) 228 (68%)  
 Missing 18 (51%) 71 (21%)  
Previous radiotherapy    0.838
 Yes 1 (3%) 14 (4%)  
 No 23 (66%) 261 (78%)  
 Missing 11 (31%) 59 (18%)  
Previous abdominal surgeryb    0.056
 Yes 9 (26%) 78 (23%)  
 No 9 (26%) 194 (58%)  
 Missing 17 (49%) 62 (19%)  
  1. aAllergy to penicillin; bPrevious abdominal surgery included cholecystectomy, lateral pancreaticojejunostomy