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Table 1 Characterization of population according to acute pancreatitis severity

From: Red cell distribution width and red cell distribution width to total serum calcium ratio as major predictors of severity and mortality in acute pancreatitis

Variable Severe acute pancreatitis (n = 91) Mild acute pancreatitis (n = 91) pU/pM aOR, 95 CI in M
Age (yo), μ ± σ 64.8 ± 16.3 67.9 ± 13.7 0.239/−
Male gender, n(%) 53(58.2%) 47(51.6%) 0.228/−
Alcoholism, n(%) 26(28.6%) 14(15.4%) 0.032/−
Smoking, n(%) 0(0.0%) 5(5.5%) 0.023/−
Hospital stay, median(IQR) 1.3(2–83) 8.0(2–25) 0.001/−
Comorbiditiesa, n(%) 75(82.4%) 83(91.2%) 0.08/−
 Hypothyroidism 2(2.2%) 9(9.9%) 0.029/−
 Cerebral vascular accident 9(9.9%) 0(0.0%) 0.002/−
 Chronic renal disease 10(11.0%) 3(3.3%) 0.004/−
Laboratory and gasometrical parameters
 WBC count (cells/mm3), μ ± σ 15,630.0 ± 9030.0 31,165.0 ± 1631.7 0.001/−
 AST (IU/L), μ ± σ 193.5 ± 164.1 778.9 ± 354.6 0.003/−
 ALT (IU/L), μ ± σ 249.7 ± 180.3 445.5 ± 252.8 0.129/−
 Total bilirubin (mg/dL), μ ± σ 2.7 ± 2.6 2.2 ± 1.9 0.363/−
 Platelet count (cells/mm3), μ ± σ 212.2 ± 87.1 208.8 ± 72.8 0.975/−
 BUN (mg/dL), μ ± σ 26.6 ± 17.1 19.4 ± 8.8 0.009/< 0.001 1.002, [1.001;1.007]
 Creatinine (mg/dL), μ ± σ 1.5 ± 1.3 0.9 ± 0.3 < 0.001/−
 INR, μ ± σ 3.0 ± 1.6 1.4 ± 0.2 < 0.001/−
 Albumin (g/dL), μ ± σ 3.6 ± 0.6 4.0 ± 0.7 < 0.001/−
 LDH (IU/L), μ ± σ 503.0 ± 403.7 406.8 ± 305.4 < 0.001/−
 Serum glucose (mg/dL), μ ± σ 168.0 ± 72.6 130.9 ± 35.5 < 0.001/< 0.001 1.002, [1.001;1.317]
 Hemoglobin (mg/dL), μ ± σ 13.8 ± 2.6 13.5 ± 1.4 0.406/−
 Hematocrit (%), μ ± σ 41.5 ± 7.0 40.2 ± 4.3 0.285/−
 Serum amylase (IU/L), μ ± σ 1315.2 ± 1163.3 2049.2 ± 1715.0 0.398/−
 CRP0h (mg/dL), μ ± σ 10.9 ± 9.2 5.0 ± 3.3 < 0.001/−
 CRP24h (mg/dL), μ ± σ 21.1 ± 11.6 11.3 ± 5.8 < 0.001/−
 Lactate (mg/dL), μ ± σ 2.8 ± 1.7 1.5 ± 1.0 < 0.001/−
 D-dimers (μg/mL), μ ± σ 6.6 ± 6.5 1.5 ± 0.3 0.192/−
 Total serum calcium (mg/dL), μ ± σ 8.2 ± 1.2 9.6 ± 0.4 < 0.001/−
 RDW0h (%), μ ± σ 14.6 ± 1.3 12.7 ± 0.5 < 0.001/< 0.001 1.129, [1.065;1.192]
 RDW24h (%), μ ± σ 14.3 ± 1.9 12.8 ± 0.5 < 0.001/0.005 1.015, [1.003;1.055]
 RDW0h-to-total serum calcium ratio, μ ± σ 1.8 ± 0.4 1.3 ± 0.1 < 0.001/< 0.001 1.556, [1.356;1.756]
 RDW0h-to-platelets ratio, μ ± σ 0.08 ± 0.03 0.07 ± 0.02 0.03/−
Prognostic scores
 Ranson score, μ ± σ 2.6 ± 1.2 1.5 ± 0.9 < 0.001/< 0.001 1.043, [1.001;1.088]
 BISAP score, μ ± σ 1.7 ± 0.9 1.0 ± 0.7 < 0.001/< 0.001 1.028, [1.016;1.092]
 Modified Marshall score, μ ± σ 0.8 ± 0.7 0.0 ± 0.0 < 0.001/< 0.001 1.184, [1.112;1.256]
  1. ALT alanine aminotransferase, AST aspartate aminotransferase, aOR adjusted odds ratio, BUN blood urea nitrogen, CRP0h C-reactive protein at 0 h, CRP24h C-reactive protein at 24 h, CI confidence interval, INR international normalized ratio, IQR interquartile range, LDH lactate dehydrogenase, M multivariate analysis, RDW0h red cell distribution width at 0 h, RDW24h red cell distribution width at 24 h, U univariate analysis, WBC white blood cells
  2. a Only presented significant comorbidities in univariate analysis; Comorbidities evaluated: Neurological, cardiovascular, respiratory and gastrointestinal conditions, malignancy and immunosuppression