Skip to main content

Table 4 Association of SPARCL1 expression with clinicopathological factors of gastric GIST (n = 98)

From: Secreted protein acidic and rich in cysteine-like 1 suppresses metastasis in gastric stromal tumors

Variables SPARCL1 expression P value
SPARCL1-low SPARCL1-high
Gender    0.182
Male 10 (37.04) 37 (52.11)  
Female 17 (62.96) 34 (47.89)  
Age (years) 55.67 ± 14.11 57.89 ± 10.46 0.398
Surgical margins    0.062
R0 24 (88.89) 70 (98.59)  
Not R0 3 (11.11) 1 (1.41)  
Multivisceral resection (n, %) 7 (25.93) 2 (2.82) 0.002
Tumor rupture (n, %) 1 (3.70) 0 (0.00) 0.276
Hepatic metastasis at initial diagnosis (n, %) 5 (18.52) 0 (0.00) 0.001
Peritoneal metastasis at initial diagnosis (n, %) 7 (25.93) 0 (0.00) < 0.001
Tumor size (cm) 11.94 ± 9.04 5.63 ± 3.24 < 0.001
Mitotic count (n, %)    < 0.001
≤5/50 HPF 3 (11.11) 35 (49.30)  
6~ 10/50 HPF 9 (33.33) 20 (28.17)  
> 10/50 HPF 15 (55.56) 16 (22.54)  
NIH risk classification (n, %)    0.127
Very low 0 (0.00) 4 (5.63)  
Low 1 (3.70) 20 (28.17)  
Intermediate 4 (14.81) 22 (30.99)  
High 22 (81.48) 25 (35.21)  
  1. SPARCL1 secreted protein acidic and rich in cysteine-like protein 1, GIST gastrointestinal stromal tumors, HPF high power field, NIH National Institutes of Health, “Not R0” includes surgeries of R1 and R2 resections