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Table 3 Previous meta-analyses comparing MIPD with OPD for benign and malignant periampullary disease

From: Expanding laparoscopic pancreaticoduodenectomy to pancreatic-head and periampullary malignancy: major findings based on systematic review and meta-analysis

Variables Correa Nigri Lei Qin de Rooij Zhang Peng Shinb Shinb
Year 2014 2014 2014 2014 2016 2016 2017 2017 2017
Included studies 6 8 9 11 19 22 9 8 5
Minimally invasive method MIPD MIPD MIPD MIPD MIPD MIPD RPD LPD RPD
Total MIPD numbers 169 204 209 327 710 1018 245 450 160
POPF NS NS NS NS NS NS NS NS NS
Morbidity NS NS NS NSa N/A NS Favor RPD NS NSa
Mortality N/A NS NS NS NS NS NS N/A N/A
R0 rate Favor MIPD NS Favor MIPD NSa Favor MIPD Favor MIPD Favor RPD NS NS
Retrieved lymph nodes Favor MIPD NSa NS NS NS NSa NS NS NS
Survival N/A N/A N/A N/A N/A N/A N/A N/A N/A
Operation time Favor OPD Favor OPD Favor OPD Favor OPD Favor OPD Favor OPD NS Favor OPD Favor OPD
Blood loss Favor MIPD Favor MIPD Favor MIPD Favor MIPD Favor MIPD Favor MIPD N/A NS Favor RPD
Transfusion N/A NS Favor MIPD N/A N/A Favor MIPD N/A N/A N/A
Hospital stay (days) Favor MIPD Favor MIPD Favor MIPD Favor MIPD Favor MIPD Favor MIPD Favor RPD Favor LPD Favor RPD
  1. NS not significant, N/A not available
  2. a not significant but tended to favor MIPD
  3. b one separate study