Obesity increases the risk of erosive esophagitis but metabolic unhealthiness alone does not: a large-scale cross-sectional study

Table 3 Univariable risk factors of erosive esophagitis

	Odds ratio	95% Confidence interval	P
Age	0.996	0.990–1.002	0.193
Male	3.848	3.265–4.534	< 0.001
Diabetes	1.329	1.089–1.623	0.005
Hypertension	1.343	1.152–1.566	< 0.001
Obesity	2.024	1.768–2.316	< 0.001
Coffee	1.321	1.135–1.536	< 0.001
Alcohol	2.346	2.038–2.701	< 0.001
Smoking	2.237	1.953–2.562	< 0.001
Helicobacter pylori seropositivity	0.395	0.342–0.455	< 0.001
White blood cell count	1.145	1.105–1.185	< 0.001
Fasting plasma glucose	1.006	1.004–1.008	< 0.001
Glycated hemoglobin	1.206	1.121–1.298	< 0.001
Insulin	1.027	1.017–1.037	< 0.001
HOMA-IR	1.1	1.065–1.137	< 0.001
Total cholesterol	1	0.999–1.002	0.719
Triglyceride	1.003	1.003–1.004	< 0.001
High density lipoprotein cholesterol	0.979	0.974–0.985	< 0.001
Low density lipoprotein cholesterol	1.001	0.998–1.003	0.628
Metabolic Obesity status
Metabolic healthy nonobese	1
Metabolic healthy obese	2.059	1.716–2.472	< 0.001
Metabolic unhealthy nonobese	1.469	1.203–1.794	< 0.001
Metabolic unhealthy obese	2.387	2.007–2.840	< 0.001
Metabolic abdominal obesity status
Metabolic healthy abdominal nonobese	1
Metabolic healthy abdominal obese	1.024	0.856–1.225	0.792
Metabolic unhealthy abdominal nonobese	1.578	1.298–1.919	< 0.001
Metabolic unhealthy abdominal obese	1.585	1.328–1.892	0.001

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