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Table 2 Characteristics of subjects with or without erosive esophagitis

From: Obesity increases the risk of erosive esophagitis but metabolic unhealthiness alone does not: a large-scale cross-sectional study

 

EE (−) (n = 9390)

EE (+) (n = 948)

P

Age (years)

51.7 ± 11.4

51.2 ± 11.6

0.193

Male (n, %)

4780 (50.9%)

758 (80.0%)

< 0.001

Diabetes (n, %)

963 (10.3%)

125 (13.2%)

0.005

Hypertension (n, %)

1960 (20.9%)

248 (26.2%)

< 0.001

Obesity (n, %)

2847 (30.3%)

443 (46.7%)

< 0.001

Abdominal obesity (n, %)

4040 (43.0%)

432 (45.6%)

0.119

Metabolic unhealthiness (n, %)

2895 (30.8%)

390 (41.1%)

< 0.001

Metabolic obesity status (n, %)

  

< 0.001

 Metabolic healthy nonobese

5092 (54.2%)

356 (37.6%)

 

 Metabolic healthy obese

1403 (14.9%)

202 (21.3%)

 Metabolic unhealthy nonobese

1451 (15.5%)

149 (15.7%)

 Metabolic unhealthy obese

1444 (15.4%)

241 (25.4%)

Metabolic abdominal obesity status (n, %)

  

< 0.001

 Metabolic healthy abdominal nonobese

4122 (43.9%)

351 (37.0%)

 

 Metabolic healthy abdominal obese

2373 (25.3%)

207 (21.8%)

 Metabolic unhealthy abdominal nonobese

1228 (13.1%)

165 (17.4%)

 Metabolic unhealthy abdominal obese

1667 (17.8%)

225 (23.7%)

Smoking (n, %)

3634 (38.7%)

555 (58.5%)

< 0.001

Alcohol (n, %)

4321 (46.0%)

632 (66.7%)

< 0.001

Coffee (n, %)

6386 (68.0%)

699 (73.7%)

< 0.001

Laboratory findings

 Helicobacter pylori seropositive (n, %)

5080 (54.1%)

301 (31.8%)

< 0.001

 White blood cell count (× 109/L)

5.7 ± 1.7

6.1 ± 1.8

< 0.001

 Fasting plasma glucose (mmol/L)

5.3 ± 1.3

5.5 ± 1.6

< 0.001

 Glycated hemoglobin (%)

5.6 ± 0.7

5.8 ± 0.9

< 0.001

 Insulin (pmol/L)

6.7 ± 5.5

7.8 ± 5.7

< 0.001

 HOMA-IR

1.65 ± 1.57

2.01 ± 2.05

< 0.001

 Total cholesterol (mmol/L)

5.2 ± 1.0

5.2 ± 0.9

0.719

 Triglyceride (mmol/L)

1.2 ± 0.9

1.5 ± 1.1

< 0.001

 High density lipoprotein cholesterol (mmol/L)

1.4 ± 0.3

1.3 ± 0.3

< 0.001

 Low density lipoprotein cholesterol (mmol/L)

3.2 ± 0.8

3.2 ± 0.8

0.628

  1. Data are presented as either mean ± standard deviation or as number (%)
  2. EE erosive esophagitis, HOMA-IR homeostasis model assessment of insulin resistance