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Table 1 Characteristics of subjects by metabolic obesity status

From: Obesity increases the risk of erosive esophagitis but metabolic unhealthiness alone does not: a large-scale cross-sectional study

 

MHNO

(n = 5448)

MHO

(n = 1605)

MUNO

(n = 1600)

MUO

(n = 1685)

P

Age (years)

49.5 ± 11.4

51.6 ± 11.1

56.5 ± 10.3

53.9 ± 11.2

< 0.001

Male (n, %)

2339 (42.9%)

1074 (66.9%)

921 (57.6%)

1204 (71.5%)

< 0.001

Diabetes (n, %)

153 (2.8%)

50 (3.1%)

418 (26.1%)

467 (27.7%)

< 0.001

Hypertension (n, %)

582 (10.7%)

328 (20.4%)

616 (38.5%)

682 (40.5%)

< 0.001

BMI (kg/m2)

21.7 ± 2.0

26.8 ± 1.7

22.9 ± 1.6

27.6 ± 2.3

< 0.001

Abdominal obesity (n, %)

1454 (26.7%)

1127 (70.2%)

574 (35.9%)

1320 (78.3%)

< 0.001

Coffee (n, %)

3664 (67.3%)

1156 (72.0%)

1025 (64.1%)

1240 (73.6%)

< 0.001

Alcohol (n, %)

2337 (42.9%)

932 (58.1%)

735 (45.9%)

949 (56.3%)

< 0.001

Smoking (n, %)

1883 (34.6%)

705 (43.9%)

715 (44.7%)

886 (52.6%)

< 0.001

H.pylori seropositive (n, %)

2757 (50.6%)

839 (52.3%)

863 (53.9%)

922 (54.7%)

0.008

WBC count (×  109/L)

5.4 ± 1.7

5.7 ± 1.6

6.0 ± 1.8

6.3 ± 1.7

< 0.001

FPG (mmol/L)

4.9 ± 0.8

5.1 ± 0.7

6.1 ± 1.8

6.2 ± 1.6

< 0.001

HbA1c (%)

5.4 ± 0.5

5.5 ± 0.5

6.0 ± 1.1

6.1 ± 1.0

< 0.001

Insulin (pmol/L)

34.7 ± 21.5

50.0 ± 27.1

54.9 ± 38.9

80.6 ± 61.8

< 0.001

HOMA-IR

1.1 ± 0.7

1.6 ± 0.9

2.2 ± 2.0

3.2 ± 2.5

< 0.001

Total cholesterol (mmol/L)

5.1 ± 0.9

5.2 ± 0.9

5.2 ± 1.0

5.2 ± 1.1

< 0.001

Triglyceride (mmol/L)

0.9 ± 0.5

1.1 ± 0.6

1.8 ± 1.1

2.0 ± 1.3

< 0.001

HDL-cholesterol (mmol/L)

1.5 ± 0.3

1.3 ± 0.3

1.2 ± 0.3

1.1 ± 0.3

< 0.001

LDL-cholesterol (mmol/L)

3.1 ± 0.8

3.3 ± 0.8

3.1 ± 0.9

3.2 ± 0.9

< 0.001

EE (n, %)

356 (6.5%)

202 (12.6%)

149 (9.3%)

241 (14.3%)

< 0.001

EE grade (n, %)

    

< 0.001

 A

310 (5.7%)

172 (10.7%)

127 (7.9%)

186 (11.0%)

 

 B

37 (0.1%)

27 (1.7%)

19 (1.2%)

45 (2.7%)

 C or D

9 (0.2%)

3 (0.2%)

3 (0.2%)

10 (0.6%)

  1. Data are presented as either mean ± standard deviation or as number (%)
  2. BMI body mass index, EE erosive esophagitis, FPG fasting plasma glucose, HbA1c glycated hemoglobin, HDL high density lipoprotein, HOMA-IR homeostasis model assessment of insulin resistance, MHNO metabolic healthy nonobese, MHO metabolic healthy obese, MUNO metabolic unhealthy nonobese, MUO metabolic unhealthy obese, LDL low density lipoprotein, TC total cholesterol, WBC white blood cell