Skip to main content

Table 5 Clinicopathologic features of patients and tumors according to the sedation method used for endoscopic submucosal dissection

From: Endoscopic submucosal dissection under general anesthesia for superficial esophageal squamous cell carcinoma is associated with better clinical outcomes

Variables Conscious sedation (n = 93) General anesthesia (n = 82) p-value
Age (years) 63.7 ± 8.0 65.3 ± 7.6 0.191
Gender, male 85 (91.4) 77 (93.9) 0.577
Tumor location    0.064
 Upper thoracic 4 (4.3) 9 (11.0)  
 Middle thoracic 21 (22.6) 25 (30.5)  
 Lower thoracic 65 (69.9) 48 (58.5)  
 Esophagogastric junction 3 (3.2) 0 (0.0)  
Tumor morphology    <  0.001
 IIa 6 (6.5) 20 (24.4)  
 IIb 77 (82.8) 48 (58.5)  
 IIc 10 (10.8) 11 (13.4)  
 Mixed 0 (0.0) 3 (3.7)  
Gross tumor size (cm) 1.2 ± 0.6 1.9 ± 1.0 <  0.001
Pathologic tumor size (cm) 1.2 ± 0.6 1.8 ± 0.9 <  0.001
Circumferential size of the tumor (of lumen)    0.005
 <  1/4 24 (25.8) 26 (31.7)  
 ≥ 1/4, <  1/2 66 (71.0) 43 (52.4)  
 ≥ 1/2, <  3/4 3 (3.2) 13 (15.9)  
 ≥ 3/4 0 (0.0) 0 (0.0)  
Circumferential size of the post-ESD mucosal defect (of lumen)    < 0.001
 < 1/4 4 (4.3) 1 (1.2)  
 ≥ 1/4, < 1/2 49 (52.7) 19 (23.2)  
 ≥ 1/2, <  3/4 37 (39.8) 48 (58.5)  
 ≥ 3/4 3 (3.2) 14 (17.1)  
Depth of tumor invasion    < 0.001
 M1 20 (21.5) 6 (7.3)  
 M2 38 (40.9) 33 (40.2)  
 M3 22 (23.7) 20 (24.4)  
 SM1 9 (9.7) 1 (1.2)  
 SM2&3 4 (4.3) 22 (26.8)  
Experience of endoscopist, First 10 esophageal ESDs 38 (40.9) 13 (15.9) < 0.001
  1. Data are presented as mean ± SD or number (%) of patients or lesions