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Table 5 Clinicopathologic features of patients and tumors according to the sedation method used for endoscopic submucosal dissection

From: Endoscopic submucosal dissection under general anesthesia for superficial esophageal squamous cell carcinoma is associated with better clinical outcomes

Variables

Conscious sedation (n = 93)

General anesthesia (n = 82)

p-value

Age (years)

63.7 ± 8.0

65.3 ± 7.6

0.191

Gender, male

85 (91.4)

77 (93.9)

0.577

Tumor location

  

0.064

 Upper thoracic

4 (4.3)

9 (11.0)

 

 Middle thoracic

21 (22.6)

25 (30.5)

 

 Lower thoracic

65 (69.9)

48 (58.5)

 

 Esophagogastric junction

3 (3.2)

0 (0.0)

 

Tumor morphology

  

<  0.001

 IIa

6 (6.5)

20 (24.4)

 

 IIb

77 (82.8)

48 (58.5)

 

 IIc

10 (10.8)

11 (13.4)

 

 Mixed

0 (0.0)

3 (3.7)

 

Gross tumor size (cm)

1.2 ± 0.6

1.9 ± 1.0

<  0.001

Pathologic tumor size (cm)

1.2 ± 0.6

1.8 ± 0.9

<  0.001

Circumferential size of the tumor (of lumen)

  

0.005

 <  1/4

24 (25.8)

26 (31.7)

 

 ≥ 1/4, <  1/2

66 (71.0)

43 (52.4)

 

 ≥ 1/2, <  3/4

3 (3.2)

13 (15.9)

 

 ≥ 3/4

0 (0.0)

0 (0.0)

 

Circumferential size of the post-ESD mucosal defect (of lumen)

  

< 0.001

 < 1/4

4 (4.3)

1 (1.2)

 

 ≥ 1/4, < 1/2

49 (52.7)

19 (23.2)

 

 ≥ 1/2, <  3/4

37 (39.8)

48 (58.5)

 

 ≥ 3/4

3 (3.2)

14 (17.1)

 

Depth of tumor invasion

  

< 0.001

 M1

20 (21.5)

6 (7.3)

 

 M2

38 (40.9)

33 (40.2)

 

 M3

22 (23.7)

20 (24.4)

 

 SM1

9 (9.7)

1 (1.2)

 

 SM2&3

4 (4.3)

22 (26.8)

 

Experience of endoscopist, First 10 esophageal ESDs

38 (40.9)

13 (15.9)

< 0.001

  1. Data are presented as mean ± SD or number (%) of patients or lesions