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Fig. 3 | BMC Gastroenterology

Fig. 3

From: Impact of nutrition and rotavirus infection on the infant gut microbiota in a humanized pig model

Fig. 3

Impact of diet and the microbiota on body weight gain, diarrhea, and HRV shedding. a Body weight gain; a, b c, sufficient diet pig groups had significantly higher body weight gain than the deficient groups for HIFM+HRV challenged, GF+HRV, or HIFM+No HRV pigs respectively (P < 0.01). Bars represent standard errors. b Severity of diarrhea after HRV challenge. In black, pigs nourished with a sufficient diet; in grey, pigs nourished with a deficient diet. Diarrhea scoring was based on the phenotypic scale from 0 to − 3, where zero was for solid feces; − 1 when feces were pasty; − 2 when feces were semi-liquid; and − 3 when feces were liquid. -1.5 was the threshold where any values below were considered as typical diarrhea symptoms. a or b: deficient diet group had significantly lower diarrhea score than the sufficient diet group for the HIFM or GF pigs respectively; c: the sufficient diet HIFM group had significantly lower diarrhea score than the deficient diet HIFM group (P < 0.05). Bars represent standard errors. c HRV shedding. The letters a, b, or c indicate the cumulative log (CCFU) of the designated group significantly higher than the Deficient+GF+HRV, Sufficient+GF+HRV, or Sufficent+HIFM+HRV group at the corresponding time point, respectively (P < 0.05). Bars represent standard errors

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