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Table 2 Basal and postprandial BA and C4 serum concentrations

From: Response of fibroblast growth factor 19 and bile acid synthesis after a body weight-adjusted oral fat tolerance test in overweight and obese NAFLD patients: a non-randomized controlled pilot trial

Variables Control Overweight Obesity p-value
N (men/women) 16 (7/9) 14 (8/6) 12 (6/6) n.s.a
Bile acids (μM)
 t = 0 h 1.1 (0.8–1.7) 1.5 (0.8–2.2) 1.4 (0.9–1.7) 0.343
 t = 2 h 1.4 (1.1–4.7) 2.1 (1.2–3.8) 2.4 (1.6–4.1) 0.311
 t = 4 h 1.1 (0.7–2.0) 2.0 (1.3–2.5) 2.0 (1.0–2.3) 0.155
 t = 6 h 0.7 (0.5–1.6) 1.3 (0.8–2.0) 1.2 (0.8–1.7) 0.087
C4 (nM)
 t = 0 h 41.4 (7.0–69.2) 58.5 (12.8–91.6) 35.1 (1.2–72.3) 0.422
 t = 2 h 28.1 (7.1–49.6) 43.1 (10.0–114.0) 35.7 (1.2–118.3) 0.765
 t = 4 h 13.0 (6.8–44.7) 40.8 (21.1–99.3) 32.7 (3.3–108.0) 0.343
 t = 6 h 11.8 (4.1–34.4) 40.7 (18.1–80.1) 28.6 (3.5–82.4) 0.445
  1. All data are given as median (interquartile range), p-values: Kruskal-Wallis-test,aChi-square-test