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12.2015
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Pat. presented with liver and brain metastases.
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12.2015–03.2016
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Gemcitabine mono 1000 mg/qm d1–8 15 and selective internal radiotherapy (SIRT) analogous to the SIRCCA study protocol.Excision of the tumor in the ileum and one brain metastasis (02.2016)
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05.2016–09.2016
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Capecitabine 500 mg (2–0-2, 5d/week)
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12.09.16
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1. Cycle: Olaparib (200 mg capsules twice daily, administered orally on days 1–10 of each 21-day cycle) plus paclitaxel (175 mg/m2, administered intravenously on day 1) and carboplatin (4 mg/mL per min)
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04.10.2016
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2. Cycle: Olaparib (200 mg capsules twice daily, administered orally on days 1–10 of each 21-day cycle) plus paclitaxel (175 mg/m2, administered intravenously on day 1) and carboplatin (4 mg/mL per min)
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31.10.2016
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3. Cycle: Olaparib (100 mg capsules twice daily (reduced dosage), administered orally on days 1–10 of each 21-day cycle) plus paclitaxel (175 mg/m2, administered intravenously on day 1) and carboplatin (4 mg/mL per min)
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05.12.2016
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4. Cycle: Olaparib (100 mg capsules twice daily (reduced dosage), administered orally on days 1–10 of each 21-day cycle) plus paclitaxel (175 mg/m2, administered intravenously on day 1) and carboplatin (4 mg/mL per min)
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09.01.2017
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5. Cycle: Olaparib (100 mg capsules twice daily (reduced dosage), administered orally on days 1–10 of each 21-day cycle) plus paclitaxel (175 mg/m2, administered intravenously on day 1) and carboplatin (4 mg/mL per min)
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02.2017
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liver metastases could be removed
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12.2017
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Last CT-scan staging: still no further tumor manifestations/still no metastasis
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