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Table 2 Clinical characteristics of the populations with liver tissues enrolled in the study

From: IFI16 is involved in HBV-associated acute-on-chronic liver failure inflammation

group

NC

CHB

HBV-ACLF

case

19

59

17

sex(M/F)

ND

46/13

16/1

age(years)

ND

37(23-65)

41(29-61)

ALT(U/L)

ND

50(7-570)

40(11-156)

AST(U/L)

ND

37(15-256)

92(40-202)

Tbil(umol/L)

ND

12.1(2.6-119.9)

600.6(238-809)

INR

ND

1.03(0.87-1.35)

2.88(2.11-5.83)

PTA(%)

ND

95(63-128)

21(11-35)

Log10 (HBV DNA)

ND

5.42(0-8.54)

2(0.83-8.05)

HBsAg-positive

ND

59

17

HBsAb-positive

ND

0

0

HBeAg-positive

ND

24

2

HBeAb-positive

ND

35

15

HBcA-bpositive

ND

59

17

MELD score

ND

ND

33.33±2.02

  1. Data are shown as median and range
  2. ACLF, acute on chronic liver failure; CHB, chronic hepatitis B; ALT, alanine aminotransferase;AST, aspartate aminotransferase; Tbil, total bilirubin; HBcAb, hepatitis B c antibody; HBeAb, hepatitis B e antibody;HBeAg, hepatitis B e antigen; HBsAb, hepatitis B s antibody; HBsAg, hepatitis B s antigen; HBV, hepatitis B virus; ND, not determined; NC, normal control; PTA, prothrombin time activity. MELD Model for end-stage liver disease.