Dates | Summaries | Diagnostic Testing | Interventions |
---|---|---|---|
2002 | Found HBV infection | HBsAg, HBeAg, HBcAb positive | No antiviral treatment |
2013 | Diagnosed with cirrhosis | HBV DNA: 6.5*103 copies/ml | Telbivudine |
2013-2015.9 | HBV DNA undetected | Telbivudine | |
2015.9 | HBV DNA: 7*103 copies/ml | Telbivudine and Tenofovir | |
2015.9-2015.10 | Myalgia and hypoesthesia in both lower limbs | Telbivudine and Tenofovir | |
2015.10 | Myalgia and hypoesthesia not relieved | Adefovir | |
2015.11.17 | Myalgia and hypoesthesia not relieved | ALT 66 U/L, LDH 474 U/L, CPK 1050 U/L | Adefovir; liver-protecting treatment |
2015.11.25 | Myalgia and hypoesthesia not relieved; Chest tightness and short of breath occurred | Blood lactate 12.7 mmol/L, arterial blood gas: pH 7.25, base excess −21.1 mmol/L | Adefovir; liver-protecting treatment |
2015.11.27 (Admission) | Myalgia, hypoesthesia, chest tightness, short of breath, palpitation; Swelling and tenderness of all extremities, muscle dumbness and grade 3 strength in both lower limbs | ALT: 77 U/L, TBil: 25.2 μmol/L, CPK: 991 U/L, LDH: 509 U/L, creatine: 83 μmol/L, myoglobin: 1745 ng/ml, blood lactate: 20 mmol/L, HBV DNA undetected | Entecavir; hemodialysis; hydration; alkalization |
2015.12.4 | Nearly all symptoms relieved gradually | CPK 683 U/L, blood lactate 6.67 mmol/L | Tenofovir, Methylprednisolone 40 mg qd |
2016.1.13 | Swelling of lower limbs disappeared | CPK 47 U/L, blood lactate 3.21 mmol/L | Tenofovir |
2016.6 | Walk naturally; Dumbness in distal limbs relieved but still existed | HBV undetected | Tenofovir |