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Fig. 5 | BMC Gastroenterology

Fig. 5

From: Geranylgeranylacetone attenuates fibrogenic activity and induces apoptosis in cultured human hepatic stellate cells and reduces liver fibrosis in carbon tetrachloride-treated mice

Fig. 5

Histopathological analysis of liver specimen of male C57BL/6 J mice treated with CCl4 or CCl4 and GGA (n = 6 each). Sirius Red staining of liver tissue sections (200 × objective) and morphometric analysis of Sirius Red-stained area size (a). Immunohistochemistry for α-smooth muscle actin (SMA) in liver tissue sections (200 × objective) and morphometric analysis of SMA-positive area size (b). Bar graphs represent means ± SEM. * = P < 0.05

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