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Table 3 COX-1 and COX-2 expression based on real time polymerase chain reaction in colonic biopsies from CRN-pts and ctrls

From: Combined activity of COX-1 and COX-2 is increased in non-neoplastic colonic mucosa from colorectal neoplasia patients

  COX-1 expression, SEM COX-2 expression, SEM p-value
CRN-pts (N/n = 11/11) 0.024 ± 0.003 0.007 ± 0.002 0.012 *
Ctrls (N/n = 7/7) 0.020 ± 0.003 0.005 ± 0.002 <  0.001 *
p-value 0.24 0.43  
  1. Horizontal p-values to the right compare COX-1 expression with COX-2 expression for CRN-pts and ctrls. Vertical p-values at the bottom compare CRN-pts with ctrls for COX-1 and COX-2 expression. Total or combined expression of COX enzyme is defined as expression of COX-1 + COX-2. The combined COX expression was 0.015 ± 0.003 for CRN-pts and 0.012 ± 0.003 for ctrls; p = 0.35. CRN-pts represent values for biopsies from colorectal neoplasia patients and ctrls values are for biopsies from patients without colorectal neoplasia. N = number of patients, n = number of biopsies, in parenthesis (N/n). * p-value < 0.05