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Table 4 Univariate and multiple analyses of factors associated with the clinical response at 6 months

From: HPV positive, wild type TP53, and p16 overexpression correlate with the absence of residual tumors after chemoradiotherapy in anal squamous cell carcinoma

Characteristics OR 95% CI p aOR 95% CI p
HPV positive 31.1 1.8–531.1 0.018 31.1 1.8–531.1 0.018
Female gender 10.1 1.4–73.0 0.022    
P16 positive 8.3 2.0–34.2 0.003    
Age < 65 years 1.1 0.6–2.0 0.662    
Degree of cell differentiation I and II 1.3 0.6–2.5 0.586    
Clinical stage I and II 2.5 1.3–5.0 0.008    
T 2/3 1.2 0.5–3.1 0.675    
TP53 mutated 0.1 0.03–0.5 0.003    
  1. OR = Odds ratio; aOR = Adjusted odds ratio
  2. Statistically significant p-values are shown in bold