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Table 4 Univariate and multiple analyses of factors associated with the clinical response at 6 months

From: HPV positive, wild type TP53, and p16 overexpression correlate with the absence of residual tumors after chemoradiotherapy in anal squamous cell carcinoma

Characteristics

OR

95% CI

p

aOR

95% CI

p

HPV positive

31.1

1.8–531.1

0.018

31.1

1.8–531.1

0.018

Female gender

10.1

1.4–73.0

0.022

   

P16 positive

8.3

2.0–34.2

0.003

   

Age < 65 years

1.1

0.6–2.0

0.662

   

Degree of cell differentiation I and II

1.3

0.6–2.5

0.586

   

Clinical stage I and II

2.5

1.3–5.0

0.008

   

T 2/3

1.2

0.5–3.1

0.675

   

TP53 mutated

0.1

0.03–0.5

0.003

   
  1. OR = Odds ratio; aOR = Adjusted odds ratio
  2. Statistically significant p-values are shown in bold