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Table 3 Comparison of baseline patients’ medications between those with perforation and those without perforation by univariate analysis

From: Evaluation of risk factors for perforated peptic ulcer

  Case subjects (those with perforation) Control subjects (those without perforation) p-value
n = 136 n = 272
Medications
 Antiplatelet, n (%)    0.78
 None, n (%) 127 (93.4) 256 (94.1)  
 Aspirin, n (%) 6 (4.4) 11 (4.0)  
 Clopidogrel, n (%) 0 (0.0) 1 (0.4)  
 Limaprost alfadex, n (%) 0 (0.0) 1 (0.4)  
 Dual Antiplatelet Therapy, n (%) 3 (2.2) 3 (1.1)  
 Anticoagulant, n (%) 7 (5.1) 9 (3.3) 0.42
NSAIDs daily, n (%) 15 (11.0) 13 (4.8) 0.02
 NSAIDs rescue, n (%) 11 (8.1) 16 (5.9) 0.40
 Proton pump inhibitor, n (%) 10 (7.4) 21 (7.7) 1.00
 H2 blocker, n (%) 1 (0.7) 10 (3.7) 0.11
 Bisphosphonate, n (%) 4 (2.9) 3 (1.1) 0.23
 Spironolactone, n (%) 1 (0.7) 7 (2.6) 0.28
 Steroid, n (%) 5 (3.7) 8 (2.9) 0.77
  1. Numbers in bold indicate that the p value is less than 0.05