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Table 3 Clinical characteristics and ultrasound findings in the study subjects with chronic liver disease, by aetiology

From: Unexplained chronic liver disease in Ethiopia: a cross-sectional study

Variable

All patients (n = 150)

Aetiology known (n = 67)

Aetiology unknown (n = 83)

Symptoms

 Abdominal swelling

128 (85.3)

51 (76.1)

77 (92.8)*

 Epigastric pain

12 (80.0)

56 (83.6)

64 (77.1)

 Weight loss

119 (79.3)

54 (80.6)

65 (78.3)

 Fever

77 (51.3)

35 (52.2)

42 (50.6)

 Arthralgia/myalgia

75 (50.3)a

33 (49.3)

42 (51.2)a

 Nausea

69 (46.3)a

30 (45.5)a

39 (47.0)

 Diarrhoea

64 (42.7)

27 (40.3)

37 (44.6)

 Haematemesis

53 (35.3)

27 (40.3)

26 (31.3)

 History of jaundice

47 (31.3)

24 (35.8)

23 (27.7)

Clinical findings

 Ascites

138 (92.0)

60 (89.6)

78 (94.0)

 Splenomegaly

99 (66.0)

48 (71.6)

51 (61.4)

 Jaundice

28 (18.7)

16 (23.9)

12 (14.5)

 Caput medusae

25 (16.7)

8 (11.9)

17 (20.5)

 Hepatic encephalopathy

16 (10.7)

7 (10.4)

9 (10.8)

 Traditional scarring/burning

101 (67.3)

46 (68.7)

55 (66.3)

Ultrasound findings

 Ascites

138 (92.0)

60 (89.6)

78 (94.0)

 Smooth liver surface

4 (2.7)

3 (4.5)

1 (1.2)

 Mild uneven liver surface

44 (29.3)

15 (22.4)

29 (34.9)

 Nodular liver surface

102 (68.0)

49 (73.1)

53 (63.9)

 Heterogeneous echotexture

62 (41.3)

22 (32.8)

40 (48.2)

 Coarse echotexture

87 (58.0)

44 (65.7)

43 (51.8)

 Hepatic steatosis

1 (0.7)

1 (1.5)

0

 Periportal fibrosis

21 (14.0)

9 (13.4)

12 (14.5)

In-hospital death

9 (6.0)a

4 (6.0)

5 (6.1)a

  1. Data are presented as number (%) or as median (interquartile range) unless otherwise noted
  2. aOne observation missing
  3. *p < 0.05; significance of the difference between the aetiology known/unknown group