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Table 4 Associations of serum lipid and apolipoprotein levels with rs1042034 genotype in HCV-positive and HCV-negative subjects

From: APOB codon 4311 polymorphism is associated with hepatitis C virus infection through altered lipid metabolism

  

HCV

Genotype of rs1042034

P-value

AA (n)

GG + AG (n)

TC

(mg/dl)

+

160.9 ± 43.5 (11)

170.3 ± 30.1 (138)

0.342

–

205.7 ± 39.7 (6)

207.1 ± 32.0 (194)

0.917

LDL-C

(mg/dl)

+

86.2 ± 31.9 (11)

97.7 ± 23.2 (114)

0.134

–

121.5 ± 44.4 (6)

124.9 ± 29.1 (202)

0.779

HDL-C

(mg/dl)

+

47.1 ± 22.6 (9)

53.6 ± 18.2 (110)

0.313

–

56.5 ± 13.1 (6)

63.1 ± 17.7 (192)

0.370

TG

(mg/dl)

+

135.3 ± 66.1 (12)

106.3 ± 54.8 (127)

0.088

–

142.5 ± 31.5 (6)

97.0 ± 55.4 (194)

0.052

APOA1

(mg/dl)

+

130.6 ± 35.8 (13)

140.5 ± 31.1 (144)

0.278

–

152.3 ± 27.0 (6)

155.3 ± 29.3 (211)

0.805

APOA2

(mg/dl)

+

29.9 ± 5.6 (13)

29.6 ± 5.5 (144)

0.868

–

29.1 ± 3.5 (6)

30.9 ± 4.9 (211)

0.374

APOB

(mg/dl)

+

74.1 ± 21.8 (13)

77.7 ± 17.6 (144)

0.490

–

104.3 ± 35.3 (6)

96.5 ± 22.4 (211)

0.407

APOC2

(mg/dl)

+

2.6 ± 1.3 (13)

2.1 ± 1.0 (144)

0.056

–

4.5 ± 2.6 (6)

4.0 ± 1.6 (211)

0.505

APOC3

(mg/dl)

+

6.6 ± 2.7 (13)

6.0 ± 2.3 (144)

0.394

–

10.7 ± 3.9 (6)

9.1 ± 3.0 (211)

0.210

APOE

(mg/dl)

+

4.8 ± 2.0 (13)

4.3 ± 1.0 (144)

0.114

–

4.7 ± 1.7 (6)

4.7 ± 1.2 (211)

0.979

  1. Values are presented as mean ± standard deviation. The number of subjects available for the analysis is shown in parentheses. P-values were calculated using Student‘s t-test